是一類非細胞型微生物PPT學習教案

1、會計學1是一類非細胞型微生物是一類非細胞型微生物特性特性病毒病毒細菌細菌真菌真菌濾菌器濾菌器+ -結(jié)結(jié) 構(gòu)構(gòu)非細胞非細胞原核細胞原核細胞真核細胞真核細胞細胞壁細胞壁-+核酸類型核酸類型DNA或或RNADNARNADNARNA人工培養(yǎng)人工培養(yǎng)-+增殖方式增殖方式復制復制二分裂二分裂有性或無性有性或無性抗生素抗生素-+干擾素干擾素+-第1頁/共68頁第2頁/共68頁第3頁/共68頁第4頁/共68頁第5頁/共68頁第6頁/共68頁第7頁/共68頁第8頁/共68頁第9頁/共68頁功能功能 病毒核酸的特性：病毒核酸的特性：第10頁/共68頁第11頁/共68頁第12頁/共68頁第13頁/共68頁第14頁/

2、共68頁第15頁/共68頁dsDNA病毒復制示意圖第16頁/共68頁+ssRNA病毒復制示意圖第17頁/共68頁+ssRNA逆轉(zhuǎn)錄病毒復制示意圖第18頁/共68頁第19頁/共68頁第20頁/共68頁第21頁/共68頁第22頁/共68頁第23頁/共68頁殖第24頁/共68頁形成包涵體形成包涵體 某些病毒在宿主細胞內(nèi)增殖，其細胞質(zhì)或細胞核內(nèi)某些病毒在宿主細胞內(nèi)增殖，其細胞質(zhì)或細胞核內(nèi)會出現(xiàn)一種光學顯微鏡下可見的斑塊結(jié)構(gòu)，稱包涵體會出現(xiàn)一種光學顯微鏡下可見的斑塊結(jié)構(gòu)，稱包涵體。它是病毒在細胞內(nèi)增殖的場所。它是病毒在細胞內(nèi)增殖的場所第25頁/共68頁第26頁/共68頁第27頁/共68頁第28頁/共68

3、頁第29頁/共68頁第30頁/共68頁第31頁/共68頁第32頁/共68頁第33頁/共68頁第34頁/共68頁Embryonated eggs used to propagate viruses in the early decades of this century. Effective for the isolation & culture of many viruses e.g.influenza.第35頁/共68頁第36頁/共68頁第37頁/共68頁第38頁/共68頁第39頁/共68頁第40頁/共68頁第41頁/共68頁-ve RNApolProteins-ve RNA+ve

4、RNARI第42頁/共68頁第43頁/共68頁segmentedMultipartite, DNA as well第44頁/共68頁 + RF-strand transcribed to make mRNAand then proteins +ve strand nickedextended in rolling circle + Specifically cleavedAnd recircularised第45頁/共68頁 limportant sequences at the end of the linear virus genomes are a very common feature

5、.第46頁/共68頁formed. Endonuclease recognises and cuts at this terminal redundancy, which is then regenerated. 第47頁/共68頁第48頁/共68頁TGTGTGCACACAACACACGTGTGT第49頁/共68頁第50頁/共68頁第51頁/共68頁第52頁/共68頁第53頁/共68頁第54頁/共68頁第55頁/共68頁第56頁/共68頁Perhaps the first written record of a virus infection consists of a heiroglyph

6、from Memphis, drawn in approximately 1400BC, which depicts a temple priest called Siptah showing typical clinical signs of paralytic poliomyelitis第57頁/共68頁第58頁/共68頁第59頁/共68頁第60頁/共68頁Actinomycetes phage M1, SiphoviridaeActinomycetes phage MSP8, SiphoviridaeActinomycetes phage P-a-1, SiphoviridaeActin

7、omycetes phage R1, SiphoviridaeActinomycetes phage R2, SiphoviridaeActinomycetes phage SK1, MyoviridaeActinomycetes phage SV2, SiphoviridaeActinomycetes phage VP5, SiphoviridaeAdelaide River virus, RhabdoviridaeAdeno-associated virus 1, ParvoviridaeAdeno-associated virus 2, ParvoviridaeAdeno-associa

8、ted virus 3, ParvoviridaeAdeno-associated virus 4, ParvoviridaeAdeno-associated virus 5, ParvoviridaeAdisura atkinsoni NPV, BaculoviridaeAdoxophyes orana NPV, BaculoviridaeAedes aegypti densovirus, ParvoviridaeAedes aegypti entomopoxvirus, PoxviridaeAedes aegypti NPV, BaculoviridaeAedes albopictus d

9、ensovirus, ParvoviridaeAedes annandalei NPV, BaculoviridaeAedes atropalpus NPV, BaculoviridaeAedes epactius NPV, BaculoviridaeAedes nigromaculis NPV, BaculoviridaeAedes pseudoscutellaris densovirus, ParvoviridaeAedes scutellaris NPV, BaculoviridaeAedes sollicitans NPV, BaculoviridaeAedes taeniorhync

10、hus NPV, BaculoviridaeAedes tormentor NPV, BaculoviridaeAedes triseriatus NPV, BaculoviridaeAedia leucomelas NPV, BaculoviridaeAeromonas phage 29, MyoviridaeAeromonas phage 37, MyoviridaeAeromonas phage 43, MyoviridaeAeromonas phage 44RR2.8t, MyoviridaeAeromonas phage 51, MyoviridaeAeromonas phage 5

11、9.1, MyoviridaeAeromonas phage 65, MyoviridaeAeromonas phage Aeh1, MyoviridaeAeromonas phage Aeh2, MyoviridaeAfrican cassava mosaic virus, GeminiviridaeAfrican green monkey cytomegalovirus, HerpesviridaeAfrican green monkey HHV-like virus, HerpesviridaeAfrican green monkey polyomavirus, Papovavirida

12、eAfrican horse sickness viruses 1 to 10, ReoviridaeAfrican swine fever virus, African swine fever-like virusesAG83-1746 virus, BunyaviridaeAG83-497 virus, BunyaviridaeAgaricus bisporus virus 1, UnassignedAgaricus bisporus virus 4, PartitiviridaeAgraulis vanillae virus, TetraviridaeAgrobacterium phag

13、e PIIBNV6, MyoviridaeAgrobacterium phage PS8, SiphoviridaeAgrobacterium phage PT11, SiphoviridaeAgrobacteriurn phage Y, SiphoviridaeAgrochola helvolva cypovirus 6, ReoviridaeAgrochola lychnidis cypovirus 6, ReoviridaeAgropyron mosaic virus, PotyviridaeAgrotis exclarnationis NPV, BaculoviridaeAgrotis

14、 ipsilon NPV, BaculoviridaeAgrotis segeturn cypovirus 9, ReoviridaeAgrotis segeturn NPV, BaculoviridaeAguacate virus, BunyaviridaeAhlum water-borne virus, TombusviridaeAino virus, BunyaviridaeAkabane virus, BunyaviridaeAKR (endogenous) murine leukemia virus, RetroviridaeAlabama argillacea NPV, Bacul

15、oviridaeAlajuela virus, BunyaviridaeAlcaligenes phage 8764, SiphoviridaeAlcaligenes phage A5/A6, SiphoviridaeAlcaligenes phage A6, MyoviridaeAlcelaphine herpesvirus 1, HerpesviridaeAlcelaphine herpesvirus 2, HerpesviridaeAlenquer virus, BunyaviridaeAletia oxygala NPV, BaculoviridaeAleutian disease v

16、irus, ParvoviridaeAleutian mink disease virus, ParvoviridaeAfalfa cryptic virus 1, PartitiviridaeAlfalfa cryptic virus 2, PartitiviridaeAlfalfa latent virus, CarlavirusAlfalfa mosaic virus, BromoviridaeAlfuy virus, FlaviviridaeAllerton virus, HerpesviridaeAlligatorweed stunting virus, ClosterovirusA

17、llitrich herpesvirus 1, HerpesviridaeAllomyces arbuscula virus, UnassignedAlmeirim virus, ReoviridaeAlmpiwar virus, RhabdoviridaeAlphaea phasma NPV, BaculoviridaeAlsophila pometaria NPV, BaculoviridaeAlstroemeria mosaic virus, PotyviridaeAlstroemeria streak virus, PotyviridaeAlstroemeria virus, Carl

18、avirusAltamira virus, ReoviridaeAlteromonas phage PM2, CorticoviridaeAmapari virus, ArenaviridaeAmaranthus leaf mottle virus, PotyviridaeAmathes c-nigrum NPV, BaculoviridaeAmazon lily mosaic virus, PotyviridaeAglais urticae cypovirus 2, ReoviridaeAglais urticae cypovirus 6, ReoviridaeAglais urticae

19、NPV, BaculoviridaeAgraulis vanillae cypovirus 2, ReoviridaeAgraulis vanillae densovirus, ParvoviridaeAgraulis vanillae NPV, BaculoviridaeAndraca bipunctata GV, BaculoviridaeAneilema virus, PotyviridaeAngel fish reovirus, ReoviridaeAnhanga virus, BunyaviridaeAnhembi virus, BunyaviridaeAnisota senator

20、ia NPV, BaculoviridaeAnomala cuprea entomopoxvirus, PoxviridaeAnomis flava NPV, BaculoviridaeAnomis sabulifera NPV, BaculoviridaeAnomogyna elimata NPV, BaculoviridaeAnopheles A virus, BunyaviridaeAnopheles 8 virus, BunyaviridaeAnopheles crucians NPV, BaculoviridaeAntequera virus, BunyaviridaeAnthela

21、 varia NPV, BaculoviridaeAnthelia hyperborea NPV, BaculoviridaeAntheraea eucalypti virus, TetraviridaeAntheraea mylitta cypovirus 4, ReoviridaeAntheraea paphia NPV, BaculoviridaeAntheraea pemyi cypovirus 4, ReoviridaeAntheraea pemyi NPV, BaculoviridaeAntheraea polyphemus NPV, BaculoviridaeAntheraea

22、yamamai NPV, BaculoviridaeAnthonomus glandis PV, BaculoviridaeAnthoxan, thum latent blanching virus, HordeivirusAnthoxanthum mosaic virus, PotyviridaeAnthrenus museorum NPV, BaculoviridaeAnthriscus virus, CarlavirusAnthriscus yellows virus, SequiviridaeAnticarisia gemmatalis MNPV, BaculoviridaeAntitype xanthomista cypovirus 6, ReoviridaeAotine herpesvirus 1, HerpesviridaeAotine herpesvirus 2, HerpesviridaeAotine herpesvirus 3, HerpesviridaeApamea anceps GV, BaculoviridaeApamea