10-Deacetylbaccatin-III _Terpenoids and Glycoside - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemE10-Deacetylbaccatin IIICat. No.: HY-16565CAS No.: 32981-86-5分式: CHO分量: 544.59作靶點: Others作通路: Others儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 50 mg/mL (91.81 mM; Need ultrasonic)Mass S

2、olvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 1.8362 mL 9.1812 mL 18.3624 mL5 mM 0.3672 mL 1.8362 mL 3.6725 mL10 mM 0.1836 mL 0.9181 mL 1.8362 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內(nèi)實驗 請根據(jù)您的實驗動物和給藥式選擇適當(dāng)?shù)娜芙獍?，配制前請先配制澄清的儲備液，再依次添加助溶?為保證實驗結(jié)果的可靠性，體內(nèi)實驗的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄清的儲備液可以根據(jù)儲存條件，適當(dāng)保存；以下溶劑前的百分 指該

3、溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (4.59 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (4.59 mM); Clear solution3. 請依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (4.59 mM); Clear solution1/2

4、 Master of Small Molecules 您邊的抑制劑師www.MedChemEBIOLOGICAL ACTIVITY物活性 10-Deacetylbaccatin-III是紫杉醇制備過程中的中間體。REFERENCES1. Li S, Zhang P, Zhang M, Fu C, Yu L. Functional analysis of a WRKY transcription factor involved in transcriptional activation of theDBAT gene in Taxus chinensis. Plant Biol (Stuttg)

5、. 2013 Jan;15(1):19-26.2. Naill MC, Kolewe ME, Roberts SC. Paclitaxel uptake and transport in Taxus cell suspension cultures. Biochem Eng J. 2012 Apr15;63:50-56.3. Qayum M, Nisar M, Shah MR, et al. Analgesic and antiinflammatory activities of taxoids from Taxus wallichiana Zucc. Phytother Res.2012 A

6、pr;26(4):552-6.4. Kevin Walker and Rodney Croteau. Taxol biosynthesis: Molecular cloning of a benzoyl- CoA:taxane 2-O-benzoyltransferase cDNAfrom Taxus and functional expression in Escherichia coli. PNAS, 2000 , 97（25）：13591-13596.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-8