Bimatoprost-AGN-192024-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEBimatoprostCat. No.: HY-B0191CAS No.: 155206-00-1Synonyms: AGN 192024分式: CHNO分量: 415.57作靶點: Prostaglandin Receptor作通路: GPCR/G Protein儲存式: Powder -20C 3 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 100 mg/mL (240.63

2、mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 2.4063 mL 12.0317 mL 24.0633 mL5 mM 0.4813 mL 2.4063 mL 4.8127 mL10 mM 0.2406 mL 1.2032 mL 2.4063 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內(nèi)實驗請根據(jù)您的實驗動物和給藥式選擇適當?shù)娜芙獍?，配制前請先配制澄清的儲備液，再依次添加助溶?為保證實驗結(jié)果的可靠性，體

3、內(nèi)實驗的作液，建議您現(xiàn)現(xiàn)配，當天使；澄清的儲備液可以根據(jù)儲存條件，適當保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.75 mg/mL (6.62 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.75 mg/mL (6.62 mM); Clear solution3. 請依序添加每種溶劑： 10% DMSO 90% corn oi

4、l1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemESolubility: 2.75 mg/mL (6.62 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Bimatoprost前列腺素類似物，可作于眼內(nèi)壓和青光眼。REFERENCES1. Park J, et al. Changes to upper eyelid orbital fat from use of topical bimatoprost, travoprost, and latanoprost. Jpn J Ophthalmol. 2011Jan;55(1):22-7.2. Filippopoulos T, et al. Periorbital changes associated with topical bimatoprost. Ophthal Plast Reconstr Surg. 2008 Jul-Aug;24(4):302-7.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-589559