BAY885 - ERK5 抑制劑 - 生命科學(xué)試劑 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEBAY885Cat. No.: HY-112082CAS No.: 2307249-33-6分式: CHFNO分量: 515.53作靶點(diǎn): ERK作通路: MAPK/ERK Pathway; Stem Cell/Wnt儲(chǔ)存式: -20C, stored under argon* In solvent : -80C, 6 months; -20C, 1 month (stored underargon)溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 16.67 mg/

2、mL (32.34 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 1.9398 mL 9.6988 mL 19.3975 mL5 mM 0.3880 mL 1.9398 mL 3.8795 mL10 mM 0.1940 mL 0.9699 mL 1.9398 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請注意儲(chǔ)備液的保存式和期限。體內(nèi)實(shí)驗(yàn) 請根據(jù)您的實(shí)驗(yàn)動(dòng)物和給藥式選擇適當(dāng)?shù)娜芙獍?，配制前請先配制澄清的?chǔ)備液，再依次添加助溶劑(為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配

3、，當(dāng)天使；澄清的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 1.67 mg/mL (3.24 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 1.67 mg/mL (3.24 mM); Clear solutionBIOLOGICAL ACTIVITY1/2 Master of Small Molecule

4、s 您邊的抑制劑師www.MedChemE物活性 BAY885是新穎的 ERK5 抑制劑。IC50 & Target ERK5 ERK5REFERENCES1. Nguyen D, et al. Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido3,2- dpyrimidine Based in VitroProbe BAY-885 for the Kinase ERK5. J Med Chem. 2019 Jan 24;62(2):928-940.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: