EN460-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEEN460Cat. No.: HY-12837CAS No.: 496807-64-8分式: CHClFNO分量: 460.79作靶點(diǎn): Others作通路: Others儲(chǔ)存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 16.67 mg/mL (36.18 mM; Need ultrasonic)Mass Solvent1 mg

2、 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 2.1702 mL 10.8509 mL 21.7019 mL5 mM 0.4340 mL 2.1702 mL 4.3404 mL10 mM 0.2170 mL 1.0851 mL 2.1702 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。體內(nèi)實(shí)驗(yàn) 請(qǐng)根據(jù)您的實(shí)驗(yàn)動(dòng)物和給藥式選擇適當(dāng)?shù)娜芙獍?，配制前?qǐng)先配制澄的儲(chǔ)備液，再依次添加助溶劑(為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的

3、體積占)：1. 請(qǐng)依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 1.67 mg/mL (3.62 mM); Clear solution2. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 1.67 mg/mL (3.62 mM); Clear solutionBIOLOGICAL ACTIVITY1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE物活性 EN460ERO1分抑制劑，IC50值1.9uM。戶使本產(chǎn)品發(fā)表的科研獻(xiàn)

4、 J Exp Clin Cancer Res. 2019 Jan 31;38(1):44.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Blais JD, et al. A small molecule inhibitor of endoplasmic reticulum oxidation 1 (ERO1) with selectively reversible thiol reactivity. J BiolChem. 2010 Jul 2;285(27):20993-1003.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: