1-Linoleoyl-Glycerol-1-Linoleoyl-rac-glycerol-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemE1-Linoleoyl GlycerolCat. No.: HY-111346CAS No.: 2277-28-3Synonyms: 1-Linoleoyl-rac-glycerol; 1-Monolinolein分式: CHO分量: 354.52作靶點(diǎn): Phospholipase作通路: Metabolic Enzyme/Protease儲(chǔ)存式: Pure form -20C 3 years4C 2 yearsIn solvent -80C 6 m

2、onths-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 100 mg/mL (282.07 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 2.8207 mL 14.1036 mL 28.2072 mL5 mM 0.5641 mL 2.8207 mL 5.6414 mL10 mM 0.2821 mL 1.4104 mL 2.8207 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。體內(nèi)實(shí)驗(yàn)請(qǐng)根據(jù)您的實(shí)

3、驗(yàn)動(dòng)物和給藥式選擇適當(dāng)?shù)娜芙獍福渲魄罢?qǐng)先配制澄清的儲(chǔ)備液，再依次添加助溶劑(為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄清的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請(qǐng)依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (7.05 mM); Clear solution2. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (7.05 mM)

4、; Clear solution1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE3. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (7.05 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 1-Linoleoyl Glycerol從 S. chinensis 根中分離的種脂 酸油。IC50 & Target The (R)-1-Linoleoyl Glycerol and (S)-1-Linoleoyl Glycerol exhibit Lipo

5、protein-associated phospholipase A2(Lp-PLA2) inhibitory activities with IC50 values of 45.0 and 52.0 M, respectively 1.REFERENCES1. Lee WS, et al. Lp-PLA2 inhibitory activities of fatty acid glycerols isolated from Saururus chinensis roots. Bioorg Med Chem Lett. 2005Aug 1;15(15):3573-5.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-