Didanosine-2-3-Dideoxyinosine-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEDidanosineCat. No.: HY-B0249CAS No.: 69655-05-6Synonyms: 2,3-Dideoxyinosine; ddI分式: CHNO分量: 236.23作靶點(diǎn): HIV; Reverse Transcriptase作通路: Anti-infection儲(chǔ)存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn)

2、DMSO : 65 mg/mL (275.16 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 4.2332 mL 21.1658 mL 42.3316 mL5 mM 0.8466 mL 4.2332 mL 8.4663 mL10 mM 0.4233 mL 2.1166 mL 4.2332 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Didanosine(Vide

3、x)是逆轉(zhuǎn)錄酶抑制劑，IC50為490nM。REFERENCES1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE1. Knupp, C.A., et al., Pharmacokinetics of didanosine in patients with acquired immunodeficiency syndrome or acquired immunodeficiencysyndrome-related complex. Clin Pharmacol Ther, 1991. 49(5): p. 523-35.2. Bissuel, F., et al., Fulminant hepatitis with severe lactate acidosis in HIV-infected patients on didanosine therapy. J Intern Med, 1994.235(4): p. 367-71.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: 021-5370