CB-7921220 - Adenylate Cyclase 抑制劑 - 生命科學(xué)試劑 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemECB-7921220Cat. No.: HY-101862CAS No.: 115453-99-1分式: CHNO分量: 240.26作靶點: Adenylate Cyclase作通路: GPCR/G Protein儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 100 mg/mL (416.22 mM)* means solu

2、ble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 4.1622 mL 20.8108 mL 41.6216 mL5 mM 0.8324 mL 4.1622 mL 8.3243 mL10 mM 0.4162 mL 2.0811 mL 4.1622 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 CB-7921220是腺苷酸環(huán)化酶 (adenylate cyclase) 的抑制劑。體外研究 CB-792

3、1220 shows a degree of isoform selectivity for adenylate cyclase (AC) 1, but cannot distinguishbetween AC1 and AC6. CB-7921220 has a more consistent predicted binding position in the two virtualdocking screens, and has a binding conformation similar to ATP and P-site inhibitors, which may explain it

4、slack of selectivity between AC1 and AC6 1.1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEREFERENCES1. Brand CS, et al. Isoform selectivity of adenylyl cyclase inhibitors: characterization of known and novel compounds. J Pharmacol ExpTher. 2013 Nov;347(2):265-75.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: 02