Eperisone-Hydrochloride-racemic-Eperisone-hydrochloride-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEEperisone HydrochlorideCat. No.: HY-B1901CAS No.: 56839-43-1Synonyms: ()-Eperisone hydrochloride分式: CHClNO分量: 295.85作靶點: Others作通路: Others儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 31.

2、25 mg/mL (105.63 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 3.3801 mL 16.9005 mL 33.8009 mL5 mM 0.6760 mL 3.3801 mL 6.7602 mL10 mM 0.3380 mL 1.6900 mL 3.3801 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內(nèi)實驗請根據(jù)您的實驗動物和給藥式選擇適當(dāng)?shù)娜芙獍?，配制前請先配制澄的儲備液，再依次添加助溶?為保證實驗結(jié)果的可靠性，體內(nèi)實驗的作液，

3、建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄的儲備液可以根據(jù)儲存條件，適當(dāng)保存；以下溶劑前的百分指該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (7.03 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.08 mg/mL (7.03 mM); Clear solution3. 請依序添加每種溶劑： 10% DMSO 90% corn oil1/2 Mast

4、er of Small Molecules 您邊的抑制劑師www.MedChemESolubility: 2.08 mg/mL (7.03 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Eperisone Hydrochloride ()-Eperisone hydrochloride)種抗痙攣劑，于治療以肌僵硬和疼痛為特征的疾病。它通過放松骼肌和管平滑肌來起作，例如減少肌張，改循環(huán)和抑制疼痛反射。Eperisone Hydrochloride ()-Eperisone hydrochloride)種中樞作的肌松弛劑，抑制疼痛反射通路，具有管擴張作 1 2

5、 3。REFERENCES1. Cabitza P, et al. Efficacy and safety of eperisone in patients with low back pain: a double blind randomized study. Eur Rev MedPharmacol Sci. 2008 Jul-Aug;12(4):229-35.2. Frandisco Colomer Rusinvol, et al. Effects of Two Diffferent Doses of Eperisone in the Treatment of Acute Low Bac

6、k Pain. The Journalof Applied Research.3. Bavage S, et al. Clinical efficacy and safety of eperisone for low back pain: A systematic literature review. Pharmacol Rep. 2016Oct;68(5):903-12.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820