Streptomycin-sulfate-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEStreptomycin sulfateCat. No.: HY-B0472CAS No.: 3810-74-0分式: CHNOS.分量: 728.69作靶點(diǎn): Bacterial作通路: Anti-infection儲(chǔ)存式: 4C, protect from light* In solvent : -80C, 6 months; -20C, 1 month (protect fromlight)溶解性數(shù)據(jù)體外實(shí)驗(yàn) H2O : 33 mg/mL (45

2、.29 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 1.3723 mL 6.8616 mL 13.7233 mL5 mM 0.2745 mL 1.3723 mL 2.7447 mL10 mM 0.1372 mL 0.6862 mL 1.3723 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Streptomycin sulfate種氨糖苷類抗素，能夠抑制蛋質(zhì)的合

3、成。體外研究Strain RB1 shows enhanced susceptibility to streptomycin as the concentration of CV in the growth mediumincreases. As the CV concentration in the growth medium increases, both cytochrome aa3 levels andstreptomycin susceptibility increase. Cytochrome aa3 is necessary for accumulation of strepto

4、mycin by B.subtilis 1. Streptomycin influences tRNA selection. Streptomycin resistance mutations generally map toprotein S12 and most of these variants exhibit increased levels of discrimination in the tRNA selection1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEprocess 2.REFERENCES1. McEnroe AS,

5、et al. Correlation between cytochrome aa3 concentrations and streptomycin accumulation in Bacillus subtilis. AntimicrobAgents Chemother. 1984 Oct;26(4):507-12.2. Sharma, D., et al., Mutational analysis of S12 protein and implications for the accuracy of decoding by the ribosome. J Mol Biol, 2007.374(4): p. 1065-76.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 02