Salvianolic-acid-B-Dan-Shen-Suan-B-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemESalvianolic acid BCat. No.: HY-N1362CAS No.: 121521-90-2Synonyms: Dan Shen Suan B; Lithospermic acid B分式: CHO分量: 718.61作靶點(diǎn): Autophagy作通路: Autophagy儲(chǔ)存式: Powder -20C 3 years4C 2 years* 該產(chǎn)品在溶液狀態(tài)不穩(wěn)定，建議您現(xiàn)現(xiàn)配，即刻使。溶解性數(shù)據(jù)體外實(shí)驗(yàn) H2O : 50 mg/

2、mL (69.58 mM; ultrasonic and adjust pH to 3 with HCl)H2O : 45 mg/mL (62.62 mM)DMSO : 25 mg/mL (34.79 mM; Need ultrasonic)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 1.3916 mL 6.9579 mL 13.9158 mL5 mM 0.2783 mL 1.3916 mL 2.7832 mL10 mM 0.1392 mL 0.6958 m

3、L 1.3916 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液；該產(chǎn)品在溶液狀態(tài)不穩(wěn)定，建議您現(xiàn)現(xiàn)配，即刻使。體內(nèi)實(shí)驗(yàn)請(qǐng)根據(jù)您的實(shí)驗(yàn)動(dòng)物和給藥式選擇適當(dāng)?shù)娜芙獍?，配制前?qǐng)先配制澄的儲(chǔ)備液，再依次添加助溶劑(為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；以下溶劑前的百分指該溶劑在您配制終溶液中的體積占)：1. 請(qǐng)依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (2.89 mM); Clear solution1/2 Maste

4、r of Small Molecules 您邊的抑制劑師www.MedChemE2. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.08 mg/mL (2.89 mM); Clear solution3. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 2.08 mg/mL (2.89 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Salvianolic acid B丹參的重組分，它常來(lái)治療微循環(huán)疾病。 Phytomedicine. 2019

5、May;58:152754.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Lee YW, et al.Neuroprotective effects of salvianolic acid B on an A25-35 peptide-induced mouse model of Alzheimers disease. Eur JPharmacol. 2013 Mar 15;704(1-3):70-7.2. Liu P, et al. Effect of salvianolic acid B on c

6、ollagen production and mitogen-activated protein kinase activity in rat hepatic stellate cells.Acta Pharmacol Sin. 2002 Aug;23(8):733-8.3. Lin, Fang, et al. Salvianolic acid B protects from pulmonary microcirculation disturbance induced by lipopolysaccharide in rat. Shock.2013 Mar;39(3):317-25.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 40