《生物醫(yī)學統(tǒng)計概論》課程教學大綱

**課程教學大綱課程基本信息（CourseInformation）課程代碼（CourseCode）*學時（CreditHours）32*學分（Credits）2*課程名稱（CourseName）（中文）生物醫(yī)學統(tǒng)計概論（英文）FundamentalsofBiomedicalStatistics課程性質(CourseType)授課對象（Audience）理工科的高年級本科生或低年級研究生授課語言(LanguageofInstruction)中文*開課院系（School）數(shù)學系和生物醫(yī)學工程聯(lián)合開設先修課程（Prerequisite）高等數(shù)學*課程簡介（Description）統(tǒng)計學是一門數(shù)據(jù)科學，它是為基于實驗或觀察數(shù)據(jù)的科學發(fā)現(xiàn)提供證據(jù)而開發(fā)的分析工具。生物醫(yī)學統(tǒng)計是現(xiàn)代統(tǒng)計學的一個分支，它強調統(tǒng)計方法在生物醫(yī)學研究和臨床實驗設計上的應用。它的運用在國際上已被廣泛認為是醫(yī)學臨床研究和新藥研發(fā)必不可少的步驟。這門課程將講授基礎性的生物醫(yī)學統(tǒng)計方法，包括描述型統(tǒng)計方法，醫(yī)學中的概率計算，估計和假設檢驗的統(tǒng)計推理，量化流行病學和臨床實驗的設計。課程的目的是提供學生在基礎統(tǒng)計數(shù)據(jù)分析和生物醫(yī)學應用中研究設計的一個恰當訓練并且訓練學生如何有效地向臨床研究工作者解釋臨床數(shù)據(jù)和分析結果。學完這門課程，學生被期待掌握基于證據(jù)研究的基本準則并具備從事這類研究的基本知識和能力*課程簡介（Description）Statisticsisdatasciencethatdevelopsanalyticaltoolstoprovideevidenceforscientificfindingsbasedonexperimentalorobserveddata.BiomedicalStatisticsisabranchofmodernstatisticsthatemphasizesthestatisticalapplicationsonbiomedicalresearchanddesignofclinicaltrials.Itsimplementationhasbeengloballyrecognizedasacrucialstepinbiomedicalresearchanddevelopmentofnewdrug.Thiscoursewillcoversomebasicbiostatisticalmethodssuchasdescriptivestatistics,probabilitycalculationinmedicine,statisticalinferencesincludingestimationandhypothesistesting,quantitativeepidemiology,anddesignofclinicaltrials.Thegoalofthiscourseistoprovidestudentsanadequatetrainingin(1)performingsomebasicstatisticaldataanalysisandstudydesigninbiomedicalapplications(2)ininterpretingclinicaldataandanalyticalresultseffectivelywhencommunicatingwithclinicalresearchers.Completingthiscourse,studentsareanticipatedtounderstandthebasicprinciplesinevidence-basedstudyandtogainbasicknowledgeandskillinconductingsuchtypeofresearch.課程教學大綱（coursesyllabus）*學習目標(LearningOutcomes)1．Performingsomebasicstatisticaldataanalysisandstudydesigninbiomedicalapplications2.Interpretingclinicaldataandanalyticalresultseffectivelywhencommunicatingwithclinicalresearchers3．Understandingthephilosophyandprincipleinconductinganevidencebasedresearch*教學內容、進度安排及要求(ClassSchedule&Requirements)教學內容學時教學方式作業(yè)及要求基本要求考查方式Introduction1LectureDescriptiveStatistics4LectureHomeworkProbability7LectureHomeworkStatisticalInference-Estimation4LectureHomeworkStatisticalInference-HypothesisTesting7LectureHomeworkBasicStatisticalMethodsforEpidemiology6LectureHomeworkFinalExam3In-Class*考核方式(Grading)Homework(50%)+FinalExam(50%)*教材或參考資料(Textbooks&OtherMaterials)FundamentalsofBiostatistics(6thEdition).