慢性腎衰竭尿毒癥應(yīng)用高通量血液透析與血液透析濾過進行治療的效果比較

本文格式為Word版，下載可任意編輯——慢性腎衰竭尿毒癥應(yīng)用高通量血液透析與血液透析濾過進行治療的效果比較

目的：探討血液透析濾過、高通量血液透析應(yīng)用于慢性腎衰竭尿毒癥患者治療臨床效果。方法：選取2022年3月-2022年4月本院收治的慢性腎衰竭尿毒癥患者82例。按照隨機數(shù)字表法將其分為查看組（血液透析濾過）、對照組（高通量血液透析），各41例。對比兩組臨床療效、并發(fā)癥、治療前后的血肌酐水平、免疫球蛋白水平及肺功能指標。結(jié)果：查看組治療總有效率為97.56%，高于對照組的82.93%（字2=4.986，P=0.025），查看組并發(fā)癥發(fā)生率14.63%，低于對照組的41.46%（字2=7.312，P=0.007）；治療后，兩組血肌酐、RV水平均低于治療前，IgM、IgA、IgG、FVC、VC、TLC水平均高于治療前，且查看組血肌酐、RV水平低于對照組，IgM、IgA、IgG、FVC、VC、TLC水平均高于對照組，對比差異均有統(tǒng)計學(xué)意義（P<0.05）。結(jié)論：血液透析濾過、高通量血液透析應(yīng)用于慢性腎衰竭尿毒癥治療，均可使患者免疫功能得到有效提高，促進患者肺功能得到有效改善，但與血液透析濾過相比，高通量血液透析治療效果更加顯著。

慢性腎衰竭尿毒癥；血液透析濾過；高通量血液透析

ComparisonoftheEffectsofHighThroughputHemodialysisandHemodialysisFiltrationinChronicRenalFailureUremia/ZHONGYaocui.//MedicalInnovationofChina，2022，15（07）：008-012

Objective：Toinvestigatetheclinicaleffectofhighthroughputhemodialysisandhemodialysisfiltrationinchronicrenalfailureuremia.Method：Atotalof82patientswithchronicrenalfailureuremiatreatedinourhospitalfromMarch2022toApril2022wereselected，accordingtotherandomnumbertablemethod，theyweredividedintoobservationgroup（hemodialysisfiltration）andcontrolgroup（highthroughputhemodialysis），41casesineachgroup.Theclinicaleffects，complications，serumcreatininelevel，immunoglobulinlevelandlungfunctionindexbeforeandaftertreatmentbetweentwogroupswerecompared.Result：Thetotaleffectiverateoftreatmentinobservationgroupwas97.56%，whichwashigherthan82.93%ofcontrolgroup（字2=4.986，P=0.025）.Theincidenceofcomplicationsinobservationgroupwas14.63%，whichwaslowerthan41.46%ofcontrolgroup（字2=7.312，P=0.007）.Aftertreatment，thelevelsofserumcreatinineandRVintwogroupswerealllowerthanthoseofbeforetreatment，thelevelsofIgM，IgA，IgG，F(xiàn)VC，VCandTLCwereallhigherthanthoseofbeforetreatment，andthelevelsofserumcreatinineandRVinobservationgroupwerelowerthanthoseofcontrolgroup，thelevelsofIgM，IgA，IgG，F(xiàn)VC，VCandTLCwereallhigherthanthoseofcontrolgroup，thedifferenceswerestatisticallysignificant（P<0.05）.Conclusion：Highthroughputhemodialysisandhemodialysisfiltrationintreatmentofchronicrenalfailureuremiacaneffectivelyimprovetheimmunefunctionofpatientsandpromotetheeffectiveimprovementofpulmonaryfunction，butcomparedwithhemodialysisfiltration，theeffectofhighthroughputhemodialysisismoreremarkable.

Chronicrenalfailureuremia；