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窩溝封閉(Pit-and-fissure
sealants)Q.H.
Zhi支清惠窩溝封閉于1967年由CuetoandBuonocore首次報道,今天在牙科被廣泛應(yīng)用和推薦。兒童的點隙窩溝齲流行病學(xué)流行率:咬合面齲損占總的齲損的50.9%6~7
years
old12~14
years
old44%65%氟化物防齲對窩溝齲效果不理想窩溝是齲損易發(fā)部位咬合面的解剖結(jié)構(gòu)
容易滯留細(xì)菌有機(jī)塞、食物殘渣、菌斑阻塞窩溝點隙,阻止了氟化物的滲透較薄的牙釉質(zhì)層
對齲病易感窩溝的解剖形態(tài)淺而寬,容易清潔深而窄,容易滯留食物殘渣和細(xì)菌,窩溝的分類V型I
型不易清潔窩溝齲的發(fā)展齲損首先發(fā)生在側(cè)壁進(jìn)展至窩溝底部三角形病損進(jìn)展期預(yù)防窩溝齲的歷史回顧預(yù)防性充填法(Prophylacticodontotomy)制備I類洞,銀汞充填窩溝磨除術(shù)(Prophylacticodontoplasty)以圓鉆磨除深窩溝窩溝封閉(Pit
and
fissure
sealant)窩溝封閉的發(fā)展歷史第一代:365nm
紫外光固化,操作時間長,效果不理想第二代:Bis-GMA,
化學(xué)固化第三代:430~490nm
可見光,方便,效果好3M
Consisesealant第四代:釋氟性窩溝封閉劑Pulpdentsealant窩溝封閉適應(yīng)證萌出少于4年磨牙深的、易滯留、窄的窩溝點隙窩溝有軟化和混濁傾向其他牙齒有咬合面或光滑面齲;被封閉牙沒有鄰面齲患者接受適當(dāng)?shù)娜硇曰蚓植坑梅?,但仍然齲活躍窩溝封閉非適應(yīng)證牙齒萌出四年以上,窩溝經(jīng)常有色素沉著牙齒未完全萌出,有牙齦覆蓋除非患者為齲活躍個體,否則前磨牙不作窩溝封閉牙面窩溝淺而寬,自潔作用好患牙有鄰面齲,已有咬合面齲洞(需用充填治療)患者飲用水源不含氟,患者不能配合齲病預(yù)防計劃封閉劑成分樹脂基質(zhì)Resin
baseBis-GMA稀釋劑Thinner
(dicrease
the
viscosity) methyl
methacrylate
(MMA)et
al.引發(fā)劑Initiator self-curelight-cure
(430~490nm
visible
light)填料Filling
(increase
the
compressivestrenth,
rigidity
and
abrasive
resistance)顏色Color (easy
to
identify)酸蝕技術(shù)1955由Buonocore首先介紹35~38%磷酸恒牙30秒乳牙60
秒有機(jī)質(zhì)含量高 更耐酸酸蝕使光滑的牙釉質(zhì)表面變得不規(guī)則,增加其表面自由能。當(dāng)液體樹脂基質(zhì)置于不規(guī)則的酸蝕表面,樹脂通過毛細(xì)管作用浸入表面,單體聚合,樹脂扣入牙釉質(zhì)表面。樹脂微突的形成是封閉劑-牙釉質(zhì)粘結(jié)的基本機(jī)制。酸蝕技術(shù)牙釉質(zhì)酸蝕形成三種微結(jié)構(gòu)形式:釉小柱核心溶解,周圍不溶解釉小柱周圍溶解,核心完好不典型形態(tài)操作步驟牙面清潔Teeth
cleaning酸蝕Acid-etch沖洗吹干Washing
and
evaporation放置封閉劑Sealant
application封閉劑固化Solidify
of
sealants檢查Examination操作步驟1.
牙面清潔Teeth
cleaningcleaning
teeth
thoroughlyslow
speed
hand
piece,
mini
dental
brush
orrubbercap,pumice
powderor
dentifrices
withoutfluoride注意:不能使用脂類清潔劑或含填料的磨料必要時去除可疑齲操作步驟2.
酸蝕Acid-etch35%磷酸,2/3
牙尖斜面,恒牙30s,
乳牙60s,注意:輕輕攪拌以保證牙面接觸新鮮的酸,不能污染酸蝕面,酸蝕后的白堊色操作步驟3.
沖洗和干燥Washing
and
evaporation徹底沖洗以去除酸及反應(yīng)產(chǎn)物,以壓縮空氣或無色酒精干燥注意:不污染酸蝕面,白堊色操作步驟4.
放置封閉劑自凝性Self-cure
sealants:
mixing
for
10s
to
15s,apply
in
45s.光固化Light-cure
sealants:
apply
on
acid-etched
surfaces,fully
penetration
of
sealant
intothe
fissures,enough
thickness
to
provide
enoughcompressive
strenth,
rigidity操作步驟5.
封閉劑的固化Solidify
of
sealants自凝性self-cure
sealants:
1~2
minutes光固化light-cure
sealants:
430~490nm
visiblelight,1mm
distance,
20~40s操作步驟6.
檢測及調(diào)牙合(必要時)固化情況、粘結(jié)、氣泡、遺漏點隙、過度封閉、調(diào)牙合檢查after
3
months,
6
months
or
1
year
interval,脫落重新封閉臨床效果臨床評價保留率retention
rate=封閉劑保留的牙數(shù)/所有檢查的牙齒X100%齲降低相對有效率relative
effectiveness
of
decreased
dental
caries=(對照組患齲率-實驗組患齲率)/對照組患齲率X100%臨床效果Sealants,
by
providing
a
physical
barrier,
inhibitmicroorganisms
and
food
particles
from
collecting
in
pitsand
fissures.
Sealants
are
highly
effective
in
preventingdental
caries
in
pits
and
fissures
of
teeth
when
applied
bytrained
operators.
Sealant
should
be
placed
on
pits
andfissures
of
children’s
and
adolescents’
permanent
teethwhen
it
is
determined
that
the
tooth
or
the
patient
is
at
riskof
developing
caries.
Fissure
sealing
can
be
recommendedas
a
caries
preventive
measure.Judit
S.
Fissuresealing.
Areview,Fogorv
Sz.
2008Aug;101(4):137-46.與臨床效果有關(guān)的其他因素下頜保留率比上頜高前磨牙保留率比磨牙高大多數(shù)脫落發(fā)生在前6個月,重新封閉增加了齲病預(yù)防效果成功率因牙齒的選擇、術(shù)者的技巧、工作態(tài)度而異系統(tǒng)性評價Systematic
evaluationof
clinical
effectivenessClinical
effectiveness
of
resin
sealants
to
permanent
teethThe
relative
risks
(RR)
to
develop
dental
caries
after
resinsealants
is
0.14,
0.24,
0.30,
and
0.43
at
12,
24,
36,
and48~54
months,
respectively.
Resin
sealants
were
effectivein
caries
prevention.Abovuo-Saloranta,
et
al.
Cochrane
Database
Syst
Rev.1993Systematic
evaluation
of
clinicaleffectivenessClinical
effectiveness
of
resin
sealants
to
permanent
teethThe
relative
caries
risk
reduction
pooled
estimate
of
resin-basedsealants
on
permanent
1st
molars
was
33%
(relative
risk
=
0.67;CI
=
0.55-0.83).
The
effect
depended
on
retention
of
thesealant.
In
conclusion,
the
review
suggests
limited
evidence
thatfissure
sealing
of
1st
permanent
molars
with
resin-basedmaterials
has
a
caries-preventive
effect.
The
evidence
isincomplete
for
permanent
2nd
molars,
premolars
and
primarymolars
and
for
glass
ionomer
cements.Mejare
I,
et
al.
Caries-preventive
effect
of
fissure
sealants:
asystematic
review.
Acta
Odontol
Scand.
2003
Dec;61(6):321-30.Systematic
evaluation
of
clinicaleffectivenessClinical
effectiveness
of
resin
sealants
to
permanent
teethResin
sealants
are
effective
in
preventing
dental
caries
onocclusal
surfaces
of
permanent
teeth.The
evidence
is
incomplete
for
primary
teeth.Systematic
evaluation
of
clinicaleffectivenessClinical
effectiveness
of
glass
ionomer
(GIC)
sealantsOnly
one
parallel
study
used
GIC
sealants.
No
statistic
difference
wasfound
after
24
months.
The
retention
rates
of
different
GIC
weredifferent
and
the
evidence
was
incomplete.
Better
designed
studieswere
needed
to
prove
the
preventive
effect
of
GIC
sealants.Abovuo-Saloranta,
et
al.
Cochrane
Database
Syst
Rev.
1993Systematic
evaluation
of
clinicaleffectivenessComparision
between
self-cure
and
light-cure
sealantsno
significant
difference
between
them
regarding
theretention
rate
and
the
preventive
effectComparision
between
sealants
with
and
without
fluorideno
significant
difference
between
them
regarding
theretention
rate
and
the
preventive
effectComparision
between
GIC
and
resin
sealantsincomplete
evidence
to
show
there’s
a
differenceSystematic
evaluation
of
clinicaleffectivenessThe
accepted
reviews
provided
no
evidence
of
superiority
ofeither
sealant
material.
Six
trials
were
included
for
meta-analysis.
The
pooled
odds
ratio
was
0.96,
95%
CI
0.62-1.49,indicating
no
difference
in
the
caries-preventive
effect
of
GIC
and
resin-based
fissure
sealant
material.
This
systematic
reviewwith
meta-analysis
found
no
evidence
that
either
material
wassuperior
to
the
other
in
the
prevention
of
dental
caries.
Thus,bothmaterialsappearequallysuitablefor
clinicalapplicationasa
fissure
sealant
material.Yengopal
V,
Mickenautsch
S,
Bezerra
AC,
Leal
SC.Caries-preventive
effect
of
glass
ionomer
and
resin-basedfissuresealants
on
permanent
teeth:
a
meta
analysis.
J
Oral
Sci.
2009Sep;51(3):373-82.Systematic
evaluation
of
clinicaleffectivenessPit
and
fissure
sealants
for
preventing
dental
decay
in
thepermanentteeth
of
childrenandadolescents.Ahovuo-Salorant
A,
Cochrane
Database
Syst
Rev.
2008
Oct8;(4):CD001830.OBJECTIVES:The
primary
objective
of
this
review
was
to
evaluate
thecaries
prevention
of
pit
and
fissure
sealants
in
children
andadolescents.Systematic
evaluation
of
clinicaleffectivenessMAINRESULTS:Sixteen
studies
were
included
in
the
review;
7
studies
provided
datafor
comparison
of
sealant
versus
control
without
sealant
and
10studies
for
comparison
of
sealant
versussealant.Systematic
evaluation
of
clinicaleffectivenessMAINRESULTS:Five
split-mouth
studies
and
one
parallelgroup
study
with
5
to
10
yearold
children
found
a
significant
difference
in
favour
of
second
or
thirdgeneration
resin-based
sealants
on
first
permanent
molars,
comparedto
a
control
without
sealant,
witha
pooled
RRof
0.13
(95%
confidenceinterval
(CI)
0.09
to
0.20),
0.22
(95%
CI
0.15
to
0.34),
0.30
(95%CI0.22
to
0.40),
and
0.40
(95%
CI
0.31
to
0.51)
at
12,
24,
36
and
48-54months
followup,
respectively.
Further,
one
of
those
studies
with9years
of
follow
up
found
significantly
more
caries
in
the
control
groupcompared
to
resin
sealant
group;
27%
of
sealed
surfaces
weredecayed
compared
to
77%
of
surfaces
without
sealant.The
results
ofthe
studies
comparing
different
sealant
materials
wereconflicting.Systematic
evaluation
of
clinicaleffectivenessAUTHORS'
CONCLUSIONS:Sealing
is
a
recommended
procedure
to
prevent
caries
ofthe
occlusal
surfaces
of
permanent
molars.
Theeffectiveness
of
sealants
is
obvious
at
high
caries
risk
butinformation
on
the
benefits
of
sealing
specific
to
differentcaries
risks
is
lacking.影響窩溝封閉預(yù)防效果的因素窩溝封閉對預(yù)防齲病是有效的自凝性封閉劑比光固化的更有效封閉劑的預(yù)防效果隨時間遞減封閉劑和加氟聯(lián)合預(yù)防效果更好Liodra
JC,
et
al.
Factors
influencing
the
effectiveness
of
sealants-ameta-analysis,
Community
Dent
Oral
Epidermal
1993,21:261-8窩溝封閉的其他問題酸蝕后牙面的齲易感性即使封閉劑脫落,酸蝕后牙面在酸性溶液中的溶解度與未酸蝕牙面相近酸蝕后牙面唾液污染唾液污染阻止了樹脂微突的形成,造成封閉劑脫落、細(xì)菌侵入,引起齲齒以壓縮空氣、橡皮障或棉卷隔濕唾液污染后重新酸蝕窩溝封閉的其他問題早期窩溝齲的封閉酸蝕
殺死窩溝中的微生物封閉劑
阻止細(xì)菌的營養(yǎng)供應(yīng)酸蝕后少于3%細(xì)菌存活在窩溝封閉后早期齲停止進(jìn)展封閉性充填Sealant
restorationThe
sealant
restoration
is
indicated
primarily
on
theocclusal
surfaces
of
permanent
molars
and
premolars
andmay
also
be
indicated
for
primary
molars.
They
are
mostappropriate
when
the
prepared
cavity
in
a
pit
or
fissure
issmall
and
discrete.
Larger
cavities
wou
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