Penicillamine-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors ? ScreeningLibraries ? Proteinswww.MedChemEPenicillamine(Standard)Cat.No.:HY-B0300RCASNo.:52-67-5分子式:C?H??NO?S分子量:149.21作用靶點(diǎn):Cuproptosis;DrugMetabolite作用通路:Apoptosis;MetabolicEnzyme/Protease儲(chǔ)存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性 Penicillamine(Standard)是Penicillamine的分析標(biāo)準(zhǔn)品。本產(chǎn)品用于研究及分析應(yīng)用。Penicillamine(D-(-)-Penicillamine)是penicillin的代謝降解產(chǎn)物，可作為重金屬螯合劑使用。Penicillamine減少游離銅，減少氧化應(yīng)激。Penicillamine通過NO/NMDA途徑對(duì)癲癇發(fā)作起作用。Penicillamine是一種潛在的免疫調(diào)節(jié)劑。青霉胺可用于威爾遜氏病、類風(fēng)濕關(guān)節(jié)炎和半胱氨酸尿癥的研究。REFERENCESChenDB,et,al.Penicillamineincreasesfreecopperandenhancesoxidativestressinthebrainoftoxicmilkmice.PLoSOne.2012;7(5):e37709.RahimiN,et,al.EffectsofD-penicillamineonpentylenetetrazole-inducedseizuresinmice:involvementofnitricoxide/NMDApathways.EpilepsyBehav.2014Oct;39:42-7.MassonMJ,et,al.ToleranceinducedbylowdoseD-penicillamineinthebrownNorwayratmodelofdrug-inducedautoimmunityisimmune-mediated.ChemResToxicol.2004Jan;17(1):82-94.IshakR,et,al.Penicillaminerevisited:historicoverviewandreviewoftheclinicalusesandcutaneousadverseeffects.AmJClinDermatol.2013Jun;14(3):223-33.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax:021-5