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演講人:日期:艾滋病全英文目錄IntroductiontoAIDSClinicalManifestationsandDiagnosisofAIDSTreatmentandManagementofAIDSPreventionandControlofAIDSSocialandPsychologicalAspectsofAIDSChallengesandFuturePerspectivesonAIDS01IntroductiontoAIDSAIDS,orAcquiredImmunodeficiencySyndrome,isachronic,potentiallylife-threateningconditioncausedbythehumanimmunodeficiencyvirus(HIV)DefinitionAIDSwasfirstrecognizedintheearly1980s,initiallyamongmenwhohavesexwithmenintheUnitedStatesSincethen,ithasbecomeaglobalpanelaffectingmillionsofpeopleworldwideHistoryDefinitionandHistoryofAIDSAIDSiscausedbythehumanimmunodeficiencyvirus(HIV),whichattacksanddestroysthebody'simmunesystemCausesHIVistransmittedthroughcontactwithinfectedblood,sex,vaginalfluids,orbreastmilkCommonmodesoftransmissionincludeunprotectedsequentialintercourses,sharingofcontiguousneedsorsymmetries,andmothertochildtransmissionduringpreconcy,childbirth,orbreakfeedingTransmissionCausesandTransmissionofAIDSGlobalImpactandEpidemiologyAIDShashadadevelopingimpactglobally,specificallyinsubSaharaAfricawhereitremainstheleadingcauseofdeathamongadultsGlobalImpactAccordingtotheWorldHealthOrganization(WHO),therewereapproximately38millionpeoplelivingwithHIVgloballyin2021Ofthese,around1.5millionwerenewlyaffectedwithHIV,andnear1millionpeoplediedfromAIDSrelatedillnessesEpiology02ClinicalManifestationsandDiagnosisofAIDSFever,chills,andotherflu-likesymbolsEarlySignsandSymptomsFatigueandlossofenergySwollenlymphnodes,particularlyintheneck,armpit,orgrooveEarlySignsandSymptoms03Unexplainedweightloss01Sorethrustandheadache02RashorotherskinproblemsEarlySignsandSymptomsNightsweatsEarlySignsandSymptomsDiarraCoughandshortnessofbreadEarlySignsandSymptomsPneumocystispneumonia(PCP)ProgressiontoOpportunisticEffectsandCancers123Tuberculosis(TB)CandidaesophagitisCytomegalovirus(CMV)retinitisProgressiontoOpportunisticEffectsandCancers02030401ProgressiontoOpportunisticEffectsandCancersCryptosporidiosisHerpessimplexvirus(HSV)infectionsProgressivemultifocalleukemia(PML)LymphomaandothercancersDetectsantibodiestoHIVintheblood,indicatingexposuretothevirusHIVantibodytestMeasurestheamountofHIVintheblood,helpingtodeterminethestageofinfectionandmonitortreatmentresponseHIVRNAtest(virtualload)MeasuresthenumberofCD4cells(atypeofwhitebloodcells)intheblood,helpingtoassessimmunesystemfunctionsandpredictdiseaseprogressionCD4countAcomprehensiveassessmentofsymptoms,medicalhistory,andphysicalexaminationtodeterminethepresenceandseverityofAIDSrelatedillnessesClinicalevaluationDiagnosticCriteriaandTestingMethods03TreatmentandManagementofAIDSCombinationofdrugsARTinvolvestheuseofacombinationofantiviraldrugstosuppressthereplicationofHIVinthebodyReducingvirtualloadTheaimofARTistoreducetheamountofvirusinthebloodtoundetectablelevels,improvingthehealthoftheindividualandreducingtheriskoftransmissionLifelongtreatmentARTiscommonlyalifelongtreatmentastheviruscanbereboundiftreatmentisstoppedAntiviralTherapy(ART)PreventivemeasuresPeoplewithAIDSareatincreasedriskofdevelopingopportunisticinfectionsandcancertypesPreventivemeasuressuchasvacuum,prophylacticmedicine,andlifestylemodificationscanhelpreducetheserisksEarlydiagnosisandtreatmentEarlydiagnosisandprompttreatmentofopportunisticinfectionsandcancercanimprovesurvivalratesandqualityoflifeRegularscreeningRegularscreeningforcommonopportunisticinfectionsandcancerisrecommendedforpeoplewithAIDSManagingOpportunisticEffectsandCancersPalliativecareaimstoimprovethequalityoflifeofpeoplewithAIDSbymanagingsymptoms,relievingpain,andimprovingpsychologicalandspiritualsupportPeoplewithAIDSmayrequirearangeofsupportingservicessuchascoaching,financialassistance,andhomebasedcareTheseservicescanhelpindividualsscopewiththephysical,emotional,andsocialchallengesoflivingwithAIDSAmultidisciplinaryteamapproachinvolvinghealthcareprofessionalsfromdifferentbackgroundscanprovidecomprehensivecareandsupporttopeoplewithAIDSPalliativecareSupportingservicesMultidisciplinaryteamapproachPalliativeCareandSupportingServices04PreventionandControlofAIDSEducationandAwarenessIncreasingknowledgeandunderstandingofAIDSthroughcomprehensiveindividualeducationprograms,mediacampaigns,andcommunityoutreachCondomPromotionandDistributionEncouragingtheuseofCondomsandmakingthemwidelyavailablethroughvariouschannelssuchasschools,healthclinics,andcommunitycentersHarmReductionImplementingstrategiestoreducetheriskofHIVtransmissionamongpeoplewhoinvestindrugs,suchasneededandsystolicprograms,opioidsubstitutiontherapy,andoverdosepreventionPrimaryPreventionStrategiesSecondaryPreventionMeasuresOfferingantiviraltherapy(ART)toprospectivewomenwithHIVtoreducetheriskoftransmissiontotheirfansPreventingMothertoChildTransmissionFacilitiesaccesstoHIVtestingandcounselingservices,andsourcingregulartestingamonghighriskgroupsEarlyDetectionandDiagnosisEnsuringthatindividualswhotestpositiveforHIVarelinkedtoappropriatemedicalcareandtreatmentservicesLinkagetoCareandTreatmentManagingHIV/AIDSrelatedcomplicationsProvidingcomprehensivemedicalcareandtreatmentforindividualswithHIV/AIDStomanageopportunisticinfections,complications,anddrugsideeffectsPsychosocialSupportOfferingcounseling,psychotherapy,andsupportgroupstohelpindividualscoverwiththeemotionalandpsychologicalimpactofHIV/AIDSRehabilitationandReintegrationAssistingindividualswithHIV/AIDStoretaintheirphysical,mental,andsocialfunctionsthroughrehabilitationprogramsandreintegrationintosocietyTertiaryPreventionandRehabilitation05SocialandPsychologicalAspectsofAIDSNegativeStereotypingPeoplewithAIDSoftenfacenegativeStereotypesandassessmentsabouttheircharacters,behavior,andlifestyleDiscriminationinEmploymentandEducationManypeoplewithAIDSexperiencediscriminationintheworkplaceandeducationalinstitutions,limitingtheiropportunitiesforemploymentandadvancementSocialIsolationThefearofsigmaanddiscriminationcanleadpeoplewithAIDStoisolatethemselvesfromsociety,resultinginlonelinessandsocialexclusionStigmaandDiscriminationAgainstPeoplewithAIDSEmotionalDistress01ThediagnosisofAIDScancausesignificantemotionalstress,includingfear,anxiety,depression,andhopelessnessImpactonFamilyRelationships02Thediseasecanstrainfamilyrelationships,asfamilymembersmaystruggletoscopewiththeemotionalandpracticalimplicationsofthediagnosisGuildandShape03SomepeoplewithAIDSmayexperiencefeelingsofguideandshape,whichcanfurtherexaggeratetheiremotionalstressPsychologicalImpactonPatientsandTheirFamiliesSocialSupportSystemsandResourcesAvailableSupportGroups:ManycommunitieshavesupportgroupsforpeoplewithAIDS,providingasafespacetoshareexperiences,seekadvice,andreceiveemotionalsupportFinancialandLegalAssistance:TherearealsoresourcesavailabletoprovidefinancialandlegalassistancetopeoplewithAIDS,helpingthemnavigatethecomplexissuesrelatedtotheirhealthandwellbeingCounselingandPsychology:ProfessionalcounselingandpsychologycanhelppeoplewithAIDSandtheirfamilyscopewiththeemotionalchallengesofthediseaseEducationalPrograms:EducationalprogramsaboutAIDScanhelpreducestigmaanddiscriminationbyincreasingunderstandingandawarenessofthedisease06ChallengesandFuturePerspectivesonAIDSDrugResistanceTheemergencyofdrugresistantstrainsofHIVpresentationsisasignificantchallengeintreatingandmanagingAIDSAccesstoCareManyindividualslivingwithAIDSfacebarrierstoaccessqualityhealth,includingcost,sigma,andlimitedavailabilityofprovidersComorbiditiesThepresenceofotherchronichealthconditions,suchasmentalhealthdisordersorsubstancesabove,canreplicatethetreatmentandmanagementofAIDSCurrentChallengesinTreatingandManagingAIDS要點(diǎn)三GeneTherapyResearchersareexploringtheuseofgenetherapytotargetanddestroyHIVaffectedcells,potentiallyleadingtoacureforAIDS0102VaccineDevelopmentSignifica
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