腦源性神經(jīng)營(yíng)養(yǎng)因子論文：電針足三里對(duì)大鼠

1、論丈發(fā)表專家一中國(guó)學(xué)木論如www.59168,net腦源性神經(jīng)營(yíng)養(yǎng)因子論文：電針足三里對(duì)大鼠摘要：目的：探討電針對(duì)運(yùn)動(dòng)力竭模型大鼠hpa軸通路和海馬神經(jīng)營(yíng)養(yǎng)因子的影響。方法：將60只雄性sd大鼠隨機(jī)分為對(duì)照組、運(yùn)動(dòng)力竭模型組、電針治療組，每組20只，對(duì)照組自由進(jìn)食和飲水，運(yùn)動(dòng)力竭模型組進(jìn)行游泳訓(xùn)練，電針組大鼠游泳訓(xùn)練后進(jìn)行電針實(shí)驗(yàn)。采用放射免疫分析法測(cè)定大鼠下丘腦erf，垂體acth，腎上腺、血清cort并檢測(cè)腦源性神經(jīng)營(yíng)養(yǎng)因子含量。結(jié)果：運(yùn)動(dòng)力竭模型組動(dòng)物下丘腦erf，腎上腺、血清cort含量較對(duì)照組有顯著升高，電針治療可使運(yùn)動(dòng)后動(dòng)物下丘腦erf，腎上腺、血清cort含量顯著下降。與對(duì)照組相

2、比，模型組大鼠海馬有明顯的bdnf陽(yáng)性細(xì)胞的表達(dá)。電針組接近正常。結(jié)論：電針可明顯改善運(yùn)動(dòng)力竭模型大鼠hpa軸和海馬bdnf，對(duì)電針治療組大鼠的運(yùn)動(dòng)疲勞有良性調(diào)整作用。關(guān)鍵詞：運(yùn)動(dòng)力竭模型；電針；hpa軸;腦源性神經(jīng)營(yíng)養(yǎng)因子effectofelectroacupunctureinhippocampusonthehypothalamus-pituitary-adrenalaxis-gluandbrain-derivedneurotrophicfactorinmicetanxin-li1，sungang2，huti3(1.xiangtanuniversity，xiangtan411105，huna

3、nchina；2.collegeofphycicaleducation,centralsouth論文發(fā)表專素一中國(guó)學(xué)木論文網(wǎng)vww.59168,netuniversityofforestryandtechnology,changsha410008,hunanchina;3.collegeofphysicaleducation,hunanuniversityofscienceandtechnology,xiangtan411201,hunanchina)abstract:objective:tostudytheeffectsofelectroacupunctureonthehypothalamu

4、s-pituitaryadrenalaxisandbrain-derivedneurotropicfactorinhippocampusinexhaustedmiceofswimming.methods:60micewererandomlydividedinto3groups,thecontrolgroup,exhaustedgroupandtheelectroacupuncturegroup.radioimmunoassaymethodwasadoptedinthedeterminationofhypothalamuscrf,pituitaryacth,thecortinadrenaland

5、serumandtheexpressionofbdnfinhippocampus.results:ascomparedwiththecontrolgroup,exhaustedswimmingcouldmarkedlyenhancethehypothalamuscrf,thecortinadrenalandserum;electroacupuncturereducedthecontentsofhypothalamuscrf,thecortinadrenalandserumintheelectroacupuncturegroup.thebdnfinhippocampusneuronsofelec

6、troacupuncturegroupissignificantlyincreasedindividuallycomparedwiththecontrolgroup.thebdnfinhippocampusneuronsof論丈發(fā)表專家一中國(guó)學(xué)木論文網(wǎng)www.59168,netelectroacupunctu-regroupisclosetothecontrolgroup.conclusion:electroacupuncturecouldimprovethehypoththalamuspitu-itary-adrenalaxisandtheexpressionofbdnfinhippocam

7、pusneuronsinexhaustedmiceofswimming.electroacupuncturehasabenignregulatingeffectonsportsfatigueofexhaustedmiceofswimming.keywords:exhaustedmodel;electroacupuncture;hpa:brain-derivedneurotropicfactor隨著現(xiàn)代競(jìng)技運(yùn)動(dòng)水平的不斷提高，運(yùn)動(dòng)員在訓(xùn)練和比賽中承受的負(fù)荷量和負(fù)荷強(qiáng)度也在不斷增大，這就增加了出現(xiàn)運(yùn)動(dòng)性疲勞的機(jī)會(huì)。如何運(yùn)用合理的方法和手段，盡快緩解運(yùn)動(dòng)性疲勞，提高運(yùn)動(dòng)員的機(jī)能水平和運(yùn)動(dòng)成績(jī)，成為國(guó)內(nèi)外運(yùn)動(dòng)醫(yī)學(xué)工作者關(guān)注和研究的焦點(diǎn)。與藥物及營(yíng)養(yǎng)補(bǔ)劑相比，我國(guó)傳統(tǒng)中醫(yī)的針刺療法在改善運(yùn)動(dòng)員的機(jī)能水平、提高運(yùn)動(dòng)成績(jī)、緩解運(yùn)動(dòng)性疲勞等方面具有安全、有效、無(wú)毒副作用等特點(diǎn)1,它具有整體性、雙向性和良性調(diào)節(jié)作用，可以疏通經(jīng)絡(luò)、調(diào)和陰