Vigabatrin-Hydrochloride-γ-Vinyl-GABA-hydrochloride-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEVigabatrin HydrochlorideCat. No.: HY-B0033CAS No.: 1391054-02-6Synonyms: -Vinyl-GABA hydrochloride分式: CHClNO分量: 165.62作靶點(diǎn): GABA Receptor作通路: Membrane Transporter/Ion Channel; Neuronal Signaling儲(chǔ)存式: Powder -20C 3 years4C 2 yearsI

2、n solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 27.5 mg/mL (166.04 mM; Need ultrasonic and warming)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 6.0379 mL 30.1896 mL 60.3792 mL5 mM 1.2076 mL 6.0379 mL 12.0758 mL10 mM 0.6038 mL 3.0190 mL 6.0379 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請注意儲(chǔ)備液的保存式和期限。B

3、IOLOGICAL ACTIVITY物活性 Vigabatrin 鹽酸鹽(-Vinyl-GABA; Sabril)是GABA的結(jié)構(gòu)類似物，能不可逆地抑制GABA氨基轉(zhuǎn)移酶對GABA的分解代謝。REFERENCES1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE1. Broeer, et al. Vigabatrin for focal drug delivery in epilepsy: Bilateral microinfusion into the subthalamic nucleus is more effective thanintr

4、anigral or systemic administration in a rat seizure model. Neurobiology of Disease (2012), 46(2), 362-376.2. Gaily, Eija Vigabatrin monotherapy for infantile spasms. Expert Review of Neurotherapeutics (2012), 12(3), 275-286.3. Russo, et al. Vigabatrin has antiepileptogenic and antidepressant effects in an animal model of epilepsy and depression comorbidity.Behavioural Brain Research (2011), 225(1), 373-376.4. VigabatrinMcePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;/p>