CYT-1010 - Mu-opioid Receptor Agonist - 生命科學(xué)試劑 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemECYT-1010Cat. No.: HY-123534CAS No.: 213769-33-6分式: CHNO分量: 624.73作靶點(diǎn): Opioid Receptor作通路: GPCR/G Protein; Neuronal Signaling儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 125 mg/mL (200.09

2、 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 1.6007 mL 8.0035 mL 16.0069 mL5 mM 0.3201 mL 1.6007 mL 3.2014 mL10 mM 0.1601 mL 0.8003 mL 1.6007 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內(nèi)實驗 請根據(jù)您的實驗動物和給藥式選擇適當(dāng)?shù)娜芙獍福渲魄罢埾扰渲瞥蔚膬湟?，再依次添加助溶?為保證實驗結(jié)果的可靠性，體內(nèi)實驗的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄的儲備液

3、可以根據(jù)儲存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (3.33 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 2.08 mg/mL (3.33 mM); Clear solutionBIOLOGICAL ACTIVITY1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE物活性

4、CYT-1010種 mu-阿受體激動劑， 響 beta-arrestin 的募集和 cAMP 產(chǎn)抑制，EC50 值分別為 13.1nM、0.0053 nM，詳細(xì)信息請參考專利獻(xiàn) WO2013173730A2 1。IC50 & Target EC50: 13.1 nM (beta-arrestin), 0.0053 nM (cAMP) 1REFERENCES1. Theodore E. Maione, Novel therapeutic uses of mu-opiate receptor peptides. WO2013173730A2.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: 0