TTP-22 - Casein Kinase 抑制劑 - 生命科學(xué)試劑 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemETTP 22Cat. No.: HY-15479CAS No.: 329907-28-0分式: CHNOS分量: 330.42作靶點: Casein Kinase作通路: Cell Cycle/DNA Damage; Stem Cell/Wnt儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 51 mg/mL (154.35 mM

2、)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 3.0265 mL 15.1323 mL 30.2645 mL5 mM 0.6053 mL 3.0265 mL 6.0529 mL10 mM 0.3026 mL 1.5132 mL 3.0265 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 TTP 22種有效的 CK2 抑制劑，IC50 和 Ki 值分別為 100 nM

3、和 40 nM。IC50 & Target CK2100 nM (IC50)體外研究TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM. TTP 22 shows no effect on other1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEkianses such as Jnk3, Rock1, Tie2, Ask1, Met and FGFR1 at 10 M 1.戶使本產(chǎn)品發(fā)表的科研獻(xiàn) Patent. US20180263995A1.S

4、ee more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Golub AG, et al. Synthesis and biological evaluation of substituted (thieno2,3-dpyrimidin-4-ylthio)carboxylic acids as inhibitors of humanprotein kinase CK2. Eur J Med Chem. 2011 Mar;46(3):870-6.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: 02