SJ572403-SJ403-DataSheet-生命科學試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemESJ572403Cat. No.: HY-114712CAS No.: 19970-45-7Synonyms: SJ403分式: CHNO分量: 275.31作靶點: Others作通路: Others儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 13.89 mg/mL (50.45 mM; Need ultrasonic)M

2、ass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 3.6323 mL 18.1613 mL 36.3227 mL5 mM 0.7265 mL 3.6323 mL 7.2645 mL10 mM 0.3632 mL 1.8161 mL 3.6323 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內(nèi)實驗請根據(jù)您的實驗動物和給藥式選擇適當?shù)娜芙獍?，配制前請先配制澄清的儲備液，再依次添加助溶?為保證實驗結果的可靠性，體內(nèi)實驗的作液，建議您現(xiàn)現(xiàn)配，當天使；澄清的儲備液可以根據(jù)儲存條件，適當保存；以下溶劑前的

3、百分 指該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 1.39 mg/mL (5.05 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 1.39 mg/mL (5.05 mM); Clear solution3. 請依序添加每種溶劑： 10% DMSO 90% corn oil1/2 Master of Small Molecules 您邊的抑制劑師www.Me

4、dChemESolubility: 1.39 mg/mL (5.05 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 SJ572403 (SJ403)序蛋 p27(Kip1) 的抑制劑。p27(Kip1) CDK 的調(diào)節(jié)因，控制真核細胞分裂 1。IC50 & Target p27Kip1 1REFERENCES1. Iconaru LI, et al. Discovery of Small Molecules that Inhibit the Disordered Protein, p27(Kip1). Sci Rep. 2015 Oct 28;5:15686.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: