Glyphosate-DataSheet-生命科學(xué)試劑-MedChemExpress

Hotline:400-820-3792Inhibitors?Agonists?ScreeningLibrarieswww.MedChemEGlyphosateCat.No.:HY-B0863CASNo.:1071-83-6分?式:C?H?NO?P分?量:169.07作?靶點(diǎn):Apoptosis;Autophagy作?通路:Apoptosis;Autophagy儲(chǔ)存?式:4°C,protectfromlight*Insolvent:-80°C,6months;-20°C,1month(protectfrom

light)溶解性數(shù)據(jù)體外實(shí)驗(yàn)H2O:13.89mg/mL(82.16mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制備儲(chǔ)備液1mM5.9147mL29.5735mL59.1471mL5mM1.1829mL5.9147mL11.8294mL10mM0.5915mL2.9574mL5.9147mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存?式和期限。BIOLOGICALACTIVITY?物活性Glyphosate?種氨酸?氨酸的除草衍?物。Glyphosate靶向并阻斷?種在動(dòng)物中沒有發(fā)現(xiàn)的植物代謝途徑，莽草酸途徑，這植物合成芳?氨酸所必需的。體外研究Glyphosateisahigh-efficiency,low-toxicity,broad-spectrumherbicide.Theresiduesofglyphosate-basedherbicidesarefrequentpollutantsintheenvironment.Glyphosateexposurecouldinterferewithmouseoocytematurationbygeneratingoxidativestressandearlyapoptosis.Glyphosateinducesearlyapoptosisandautophagyinmouseoocytes[2].REFERENCES1/2MasterofSmallMolecules—您?邊的抑制劑?師www.MedChemE[1].GreimH,etal.Evaluationofcarcinogenicpotentialoftheherbicideglyphosate,drawingontumorincidencedatafromfourteenchronic/carcinogenicityrodentstudies.CritRevToxicol.2015;45(3):185-208.[2].ZhangJW,etalThetoxiceffectsandpossiblemechanismsofglyphosateonmouseoocytes.Chemosphere.2019Dec;237:124435.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792/p>