應(yīng)聘人材料匯總第二輪4.cv英文

CURRICULUM Yu,Ph.D.ResearchVirginiaG.PiperCenterforalizedDiagnosticsBiodesignInstitute,ArizonaStateUniversity,USA Phone:001-(480)688-6179();001-(480)965 001-(480)965-DateofBirth:July9, ceofBirth: Citizenship:RSEARCHINTERESTSIamleadingthePanviralProteomeProjectinCenterwiththeaimtocollectallviralgenesassociatedwithimportanthumandiseases,andtosystematicallystudy -hostinctionsbycombiningproteinmicroarray,biochemistry,bioinformatics,andcellbiologymethods.MyexpertisemainlyincludeHigh-throughput(HT)genecloningandconstructionofgenesmidProteinmicroarraytechnologyandapplicationsinstudyingproteininctionandpost-translationalmodificationaswellasintheearlydiagnosticsofdisease.AssayMAJORACHIEVEMENTSINPREVIOUSFIVEConstructedtheworldlargestPanviralProteomeViralsmidGeneRepository(1000ViralORFs,2300Clones)andRasSmallGTPaseSuperfamilysmidGeneRepository(211ORFs,523Clones)DemonstratedthegreatvalueofourviralsmidcollectioninHTviralproteinexpression,-hostinctionandearlydiagnosticsofviralinfectionBuilthuman,tuberculosisandviralproteomemicroarraysusingNAPPA(NucleicAcidProgrbleProteinArrays)technology(*Insteadofprintingpurifiedproteinsontraditionalarray,NAPPAemployssmidDNAandhumancell-proteinexpressionsystem,whichsignificantsavesthetimeandcostandenablesthedisyofthousandsofbinantproteinsonmicroarraywithintwoDevelopednewmethodstodetectprotein-proteininctionandpost-translationalmodificationonNAPPA.Theresultsrevealednovelhosttargetsforpathogeniceffectorsandnewmechanismsofpathogen-hostinction.32publications(19withfirstauthors),includingNatureProtocols,ACSNano,Mol.Cell.Proteomics,ClinicalChemistry,Theranostics,mBio,yticalChemistry,ScientificReports,ProteomicsandJBC,etc.ThetotalSCIimpactfactorishigherthan100,andthetotalcitationsis693(ScholarCitation).3HonoredwithAlexandervonHumboldtFellowAward(Germany)andYoungInvestigatorTravelintheWorldandUSHUPOconferencesREFERENCESProf.DankeXu（NanjingUniversity,）,Prof.JoshuaLaBaer(ArizonaStateUniversity,USA)andProf.MichaelSnyder(StanfordUniversity,USA)PROFESSIONALAug.2014- ResearchProject:PanviralProteomeProject,Proteinmicroarraytechnologyandapplicationinpathogen-hostin ctionstudyVirginiaG.PiperCenterforalizedDiagnostics,BiodesignInstitute,ArizonaStateUniversity,USAJan.2010-Jun. Project:Proteinmicroarraytechnologyandapplications,HTgenecloningandconstructionofgenesmidrepositoryVirginiaG.PiperCenterfor alizedDiagnostics,BiodesignInstitute,ArizonaStateUniversity,USAAdvisor:ProfessorJoshuaLaBaer(ofUS-HUPO)Nov.2007-Dec.2009 HumboldtResearchFellowProject:DevelopmentofmultiplexedimmunoassaysusingLuminexbead-basedarrayforbiomarkerdetectionNMINaturalandMedicalSciencesInstituteattheUniversityofTuebingen,GermanyAdvisor:ProfessorThomasMar.2006-Oct. AssistantResearchProject:DevelopmentofnovelproteomicstechnologyDepartmentofNewProteomicTechnology,Beijing ResearchCenter,Nov.2003- GraduateResearchProject:DevelopmentofnovelproteinarraytechnologyDepartmentofBiochemistry,BeijingInstituteofRadiationMedicine,Advisor:ProfessorDankeXuJul.2002- Project:Cloning,expressionandactivitystudyofHumanAugmenterofLiverRegeneration(hALR)GeneEngineeringLifeScienceandBiotechnologyResearchCenter,NortheastAgriculturalUniversity,Advisor:ProfessorYanhongPh.D.Biochemistry,Sep.2001-Jul.NortheastAgriculturalUniversityandBeijingInstituteofRadiationMedicine,Bachelor.Biotechnology,Sep.1997-Jul.2001NortheastAgriculturalUniversity,Harbin,XiaofangBian,PeterWiktor,PeterKahn,AlBrunner,AmritpalKhela,KailashKarthikeyan,KristiBarker,Yu,MitchMagee,CliveH.Wasserfall,DavidGibson,MadeleineERooney,JiQiu,*,JoshuaLaBaer,*Anti-ViralAntibodyProfilingbyHighDensityProteinArrays.Proteomics,insubmission.(5yearSCIIF=4.078)XiaofangBian,GarrickWallstrom,AmyDavis,JinPark,AndreaThrooph,JasonSteel,Yu,CliveWasserfall,DesmondSchatz,MarkAtkinson,JiQiu,JoshuaLaBaer.ImmunoproteomicProfilingofAnti-ViralAntibodiesinNew-OnsetType1DiabetesUsingProteinArrays,Diabetes,insubmission.(5yearSCIIF=9.105)Yu,KimberlyB.Decker,KristiBaker,M.RamonaNeunuebel,MorganGraves,NathanWestcott,HowardHang,JoshuaLaBaer,JiQiu,MatthiasP.Machner.Host-PathogenInctionProfilingUsingSelf-AssemblingHumanProteinArrays.JournalofProteomeResearch,insubmission.(5yearSCIIF=4.894)YuandJoshuaLaBaer*(2015)High-throughputidentificationofproteinswithAMPylationusingself-assembledhumanproteinmicroarrays.NatureProtocols,inpress.(5yearSCIIF=13.142)Lines,LarisaM.Dedkova,JoshuaLaBaer,SidneyM.Hecht,ShengxiChen.IncorporationofphenylalaninederivativesintohumanCD4proteintoincreasethebindingabilitywithHIVgp120protein.Bioorganic&MedicinalChemistryLetters,201424(24):5699-703.(5yearSCIIF=2.447)AndrewR.Woolery,Yu,JoshuaLaBaer,KimOrth*(2014)VariedcellularconsequencesofRacinhibitionbyVopSAMPylation.JBiolChem.2014289(47):32977-88.(5yearSCIIF=4.893)RafaelPrados-Rosales,LeandroJ.Carre?o,AnaBatista-Gonzalez,AndresBaena,ManjunathaM.VenkataswamyJiayongXu,Yu,GarrickWallstrom,D.MitcMagee,JoshuaLaBaer,JacquelineM.Achkar,WilliamR.JacobsJr,JohnChan,StevenA.PorcelliandArturoCasadevall(2014)ImmunizationwithMycobacterialmembranevesiclesprotectagainstMycobacteriumtuberculosisinmice.mBio,5(5):e01921-14.(5yearSCIIF=6.991)Wang,Wei,Yin,Linliang,Gonzalez,Laura,Wang,Shaopeng,Yu,,Eaton,Seron,Zhang,Shengtao,Chen,Hong-Yuan;LaBaer,Joshua;Tao,Nongjian(2014)Label-StudyofDrug-ReceptorBindingKinetics,ReceptorExpressionLevelsandDruginSingleCells.ScientificReports,4:6609.(5yearSCIIF=5.079)Yu,AndrewR.Woolery,PhiLuong,YiHengHao,MarkusGramme,NathanWestcott,JinPark,JieWang,XiaofangBian,GokhanDemirkan,HowardC.Hang,KimOrth,JoshuaLaBaer(2014)Clickchemistry-baseddetectionofglobalpathogen-hostAMPylationonself-assembledhumanproteinmicroarrays.Mol.Cell.Proteomics,13(11):3164-76.(5yearSCIIF=7.395)(Highlightfromthejournal)Yu,XiaofangBian,AndreaThroop,LushengSong,LerysDelMoral,JinPark,CatherineSeiler,MichaelFiacco,JasonSteel,PrestonHunter,JustinSaul,JieWang,JiQiu,JamesM.Pipas,JoshuaLaBaer(2014)ExplorationofPanviralProteome:High-ThroughputCloningandFunctionalImplicationsin-HostInctions.Theranostics,4(8):808-822.(5yearSCIIF=7.843)YuX,WallstromG,MageeDM,QiuJ,MendozaDE,WangJ,BianX,GravesM,LaBaerJ.(2013)fyingtheAntibodyBindingonProteinMicroarraysusing(5yearSCIIF=2.931)WangJ,BarkerK,SteelJ,ParkJ,SaulJ,FestaF,WallstromG,YuX,BianX,AndersonKS,FigueroaJ,LabaerJ,QiuJ.(2012)Aversatileproteinmicroarraytformenablingantibodyprofilingagainstdenaturedproteins.ProteomicsClinAppl.:10.1002/prca. .(5yearSCIIF=2.164)FestaF,RollinsSM,VattemK,HathawayM,LorenzP,MendozaEA,YuX,QiuJ,KilmerG,JensenP,WebbB,RyanET,LabaerJ.(2012)Robustmicroarrayproductionoffreshlyexpressedproteinsinahumanmilieu.ProteomicsClinAppl.2012Oct2.:10.1002/prca. .(5yearSCIIF=2.164)QingChen,ZhouminLi,XiruiZhao,Yu,MaikaVuki,WeiHe,DankeXu(2012)AHighly-SensitiveColorimetricAssayMethodforAntibodyArrayBasedonaTyramideSignalAmplificationSystem.yticalLetters,Taylor&Francis(5yearSCIIF=1.063)YanLandYuX.(2011)Complexescomprisedofadendrimerandavesicle:roleofvesiclesizeandthesurfacetensionofthevesiclemembrane.NanoScale,3(9):3812-8.(5yearSCIYuX,Schneiderhan-MarraN.andJoosT(2011)Proteinmicroarraysforalizedmedicine.BiochimicaClinica35(6):491-502.YuX,Schneiderhan-MarraN.andJoosT(2011)Proteinmicroarraysfor medicine.KlinichescheskayaLaboratornayaDiagnostika(6):49-56.YuX,Schneiderhan-MarraN.andJoosT(2011)Micropucesàprotéinesetmédecinenalisée.AnnBiolClin(Paris),69(1):17-29.(5yearSCIIF=0.4)YuX,HartmannM,WangQ,Schneiderhan-MarraN,StollD,PoetzO,KazmaierCandJoosT(2010)μFBI-amicrofluidicbead-basedimmunoassayformultiplexeddetectionofproteinsfroma?l-samplevolume.PLosOne.5(10):e13125.(5yearSCIIF=4.015)Yu,ZheYu,LiLiu,JunChi,HuanhuanHan,YingLiu,WeiHe,QihongSun,JianenGao,DankeXu(2010)High-throughputAntibodyGenerationusingMultiplexedImmunizationandImmunogenArrayysis?.JournalofBiomolecularScreening.15:1260-1267.(5yearSCIIF=2.107)YuX,Schneiderhan-MarraN.andJoosT(2010)Proteinmicroarraysforalizedmedicine.ClinicalChemistry,56(3):376-87.(5yearSCIIF=7.869)YuX,Schneiderhan-MarraN,JoosT,SchneiderE(2009)ATPTriggeredCytokineProfilesinP2X7receptorpolymorphismindividuals.ClinicalProteomics.5,Supple118.YuX,Schneiderhan-MarraN,HsuH,BaannJandJoosT.(2009)Proteinmicroarrays-systematictoolsfortheinfltorydisease.MethodsMolBiol.YanLandYuX(2009)ChargedDendrimersonLipidBilayerMembranes:InsightthroughDissipativeParticleDynamicsSimulations.Macromolecules.42,6277-6283.(5yearSCIIF=5.531)YanLandYuX(2009)EnhancedPermeabilityofChargedDendrimersacrossTenseLipidBilayerMembranes.ACSNano,3(8),2171-2176.(5yearSCIIF=13.774),趙天明,孫,,何為,許.(2008)生物素-親和素偶聯(lián)探針蛋白芯片檢測技術(shù).生物工程學(xué)報,24(3),515-520.韓，，極，何為，許.(2008)一種蛋白質(zhì)陣列新技術(shù)的研究分析試驗(yàn)室2107-YuX,XuDandChengQ(2006)Label-detectionmethodsforproteinProteomics,6,5493-5503.(5yearSCIYuX,XuD,XuD,LvR,andLiuZ(2006)Animpedancearraybiosensorforlabel-detectionofmultipleantigen-antibodybindingreactions.FrontierinBioscience,11,983-990.(5yearSCIIF=3.474)YuX,LvR,MaZ,LiuZ,HaoY,LiQ,andXuD(2006)Animpedancearraybiosensorfordetectionofthemultipleantibody-antigeninctions.yst,131,745-750.(Thecoverpaper)(5yearSCIIF=4.097)，郝艷紅，許，.(2006)蛋白在蛋白質(zhì)組學(xué)中的應(yīng)用.東北農(nóng)業(yè)大學(xué)學(xué)報.37(2):276-282.XuD,XuD,YuX,LiuZ,HeWandMaZ(2005)Label-electrochemicaldetectionforaptamer-basedarrayelectrodes.yticalChemistry.77(16),5107-5113.(OneoftheMost-AccessedArticles,July-September2005)(5yearSCIIF=5.966)HeW,YangQ,LiuZ,YuX,andXuD(2005)DNAarraybiosensorbasedonelectrochemicalhybridizationanddetection.yticalLetters,38,2567-2578.(5-yearSCIIF=1.063)XuD,MaZ,YuX,LiuZandHeW(2005)Fabricationofaproteinarrayusingmicrocontactprintinganditselectrochemicaldetection.Mol.Cell.Proteomics.4.8YuX,LvR,XuD,LiuZ,andHeW(2004)Developmentofanimpedancespectroscopyarraybiosensor.Mol.Cell.Proteomics.3.10S275.YuX,SunLandLiZ(2014)Amethodtoprepareviralproteomearrays.PatentNo.201410208385.0XuD,HanH,YuX,HeW,LiuZ,andLvR(2006)Ahigh-throughputassemblyproteinmicroarray.PatentNo.:200620119043.2XuD,YuX,HeWandLiuZ(2005)Electrochemicalarraybiosensingchip.PatentNo.:200510093674.1HONORS,PRIZESAND2014YoungInvestigatorTravelAward,US-HUPO10thAnnualConference,Seattle,2012YoungInvestigatorTravelAward,HUPO11thAnnualConference,Boston,2009YoungInvestigatorAward,HUPO8thAnnualWorldCongress,Toronto,Canada.20092007AlexandervonHumboldtresearchFellowship,AlexandervonHumboldtFoundation,Germany2007YoungInvestigatorTravelAward,YPRCandBPRC2007JointProteomicsForumontheLiverCancer,Korea OFRECOGNITIONinCNHUPO4thAnnualConferencefortheposter,Xian, OFRECOGNITIONinAnnualConferenceofBeijingInstituteofRadiationMedicinefortheposter.Beijing,2001OutstandingGraduateStudentAward.NEAU,1999OutstandingStudentAward.NEAU,1997OutstandingStudentAward.NEAU,GRANTS“DoesMycobacteriumtuberculosisusecellularmodiFICationstoAMPupvirulence?”,AdvancingResearchInnovationsandTranslational esbyStimulatingMulti-CenterResearchInitiativesRFA(2014-2015),BiodesignInstitute,ASU“AntibodybiomarkersforearlydetectionofTuberculosis”,1R01AI096213-01,USAHumboldtresearchfellowship(AlexandervonHumboldtFoundation,Germany;fellowshipID: )(2007.10-2009.12)NationalBasicResearchProgramof(No.Hi-techResearchandDevelopmentProgramof(No.2002-EDITORIALANDREVIEWEditorialBoard:2014-SOJBiochemistry,PaperReview:NatureMethods,MCP,JPR,Proteomics,Clin.Chem.,InterfaceFocus,JBS,BMCBiotech,BiomarkerInsights,ProteomicsInsightand Biochemetal.2007-Member,HumanProteomeOrganization2010-Member,TheAmericanAssociationforClinicalChemistry“GlobalidentificationofProteinAMPylationusingNAPPAarrays”,CenterforBiosensorandBioelectronics.BiodesignInstitute,Tempe,USA,2013“GlobalysisofBacteria-hostInctionbyAMPylationusingHumanNucleicAcidProgrbleProteinArrays”.inthesessionof“CharacterizationofPTMs”.USHUPO9thAnnualConference.Baltimore,USA,2013“GlobalIdentificationofProteinswithAMPylationusingHumanNucleicAcidProgrbleProteinArrays”.inthesessionof“PROTEINCAPTUREAGENTS+ARRAYS:CATCHANDDISY”.HUPO11thAnnualConference.Boston,USA,“ProteinMicroarraysforDiagnosticsDiscovery”,NationalCenterforNanoscienceandTechnology,Beijing,2012“ElucidatetheFunctionalImpactofProteinVariationsonp53-DNAInctions”.DataClub.BiodesignInstitute,ArizonaStateUniversity,Tempe,AZ,USA,2011“ProteinMicroarraysfor alizedMedicine”.BiodesignInstitute,ArizonaStateUniversity,Tempe,USA,2010“ProteinMicroarray-andApplicationsinClinicalProteomics”.BeijingProteomeResearchCenter,StateKeyLabofProteomics,Beijing,,2010“Proteinmicroarrays-andApplications”.SuzhouUniversity,Suzhou,,2009“ProteinMicroarraysfor alizedMedicine”.KeylabofyticalChemistryforLifeSciences,MinistryofEducation,NanjingUniversity,Nanjing,,2009“DevelopmentofProteinMicroarrayandtheirApplicationsinBPRC”,NMINaturalandMedicalSciencesInstituteattheUniversityofTubingen,Reutlingen,Germany,2007POSTERSATACADEMICLerysdelMoral,Yu,MitchMagee,&JoshuaLaBaer.AMPylationofHostGTPasesbyMycobacteriumtuberculosis,AnnualBiomedicalResearchConferenceforMinorityStudents(ABRCMS),2015Yu,XiaofangBian,AndreaThroop,LushengSong,LerysDelMoral,JinPark,JiQiu,JamesM.Pipas,JoshuaLaBaer.ExplorationofPanviralProteome:High-ThroughputCloningandFunctionalImplicationsin-HostInctions,USHUPO10thAnnualConference,Seattle,2014Yu;LerysDelMoral;JoshuaLabaer.ConstructionofaRasGTPaseRepositoryandFunctionalExplorationusingNucleicAcidProgrbleProteinArrays,USHUPO10thAnnualConference,Seattle,2014SyringM,XYu,TeglerT,Ober-ReynoldsB,LaBaerJ,PirotteP,PetritisK.MassSpecAnlaysisoftheAMPylome,SearchingforNovelAMPylationSites&Proteins.TGen,Phoenix,2013YangyangLiu,Yu,JunyiJiang,JingLiu,JoshuaLaBaerandYingLiu.RaisingMonoclonalAntibodyAgainstCellMembraneProteinsBasedonFlowCytometryScreeningandProteinArrayIdentification.HUPO12thAnnualConference,Yokohama,Japan,2013Yu,AndrewWoolery,MarkusGrammel,NathanWestcott,JieWang,KimOrth,HowardHangandJoshuaLaBaer.GlobalysisofBacteria-hostInctionbyAMPylationusingHumanNucleicAcidProgrbleProteinArrays.USHUPO9thAnnualConference.Baltimore,USA,2013Yu,AndrewWoolery,MarkusGrammel,NathanWestcott,JieWang,KimOrth,HowardHangandJoshuaLaBaer.GlobalIdentificationofProteinswithAMPylationusingHumanNucleicAcidProgrbleProteinArrays.HUPO11thAnnualConference.Boston,USA,2012AndrewR.Woolery,Yi-HengHao,MelanieYarbrough,PhiLuong,MarkusGrammel,Yu,HowardHang,JoshuaLaBaer,KimOrth.TestingtheHYPE:StudiesofthemlianAMPylator.ASBMBAnnualMeeting,SanDiego,2012YuX,MageeMandLaBaerJ.AntibodyProfilingofGuineaPigsResponsetoBCGvaccinationandMycobacteriumTuberculosisInfectionusingSelf-AssemblingProteinArrays.TheInternationalYearofChemistry2011(IYC2011).Phoenix,AZ,USA,NicoleSchneiderhan-Marra,StefanieRimmele,MichaelSohl,Yu,MichaelBlum,ThomasGerzabek,AlbertGeiger,AndreasMarschall,ThomasO.Joos.TheRocheNewUltrasensitiveSA-PEImprovesSandwichAssayPxMAPEurope.Amsterdam,Netherlands,YuX,Schneiderhan-MarraN,JoosT,SchneiderE.ATPTriggeredCytokineProfilesinP2X7receptorpolymorphismindividuals.HUPO8thAnnualWorldCongress,Toronto,Canada,2009SchneiderE,LorenzM,HohmannH,Schneiderhan-MarraN,YuX,JoosT,K.P2X7activationupregulatesHLA-classII,GM-CSF,IL-1βandIL-6incultureddendriticcells(cDC)andinducesmicrovesicularbody(MVB)release.MolecularTargetsforCancerTherapy:FifthBiennialMeeting.Tampa,FL,USA,2009YuX,XuD.YuZ,YuanH,LiuZ,HanHandHeW.Highthroughputassemblyproteinmicroarraysanditsapplications.YPRCandBPRC2007JointProteomicsForumontheLiverCancer.Seoul,Korea,2007YuX.Acost-effectiveproteinarrayfabricationanddetectiontechniquebasedontheagarosestamperandsilverenhancementmethod.CNHUPO4thAnnualConference,Xian,,2006XuD,MaZ,YuX,LiuZandHeW.Fabricationofaproteinarrayusingmicrocontactprintinganditselectrochemicaldetection.HUPO4thA