變態(tài)性皮膚病治療課件

變態(tài)反應性皮膚病及治療Evaluauononr.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL變鳳應性皮膚病接蝕性皮炎ContactDermatitisCD濕疹Eczema藥疹DrugeruptionEvaluauononr.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL接觸性皮炎ContactdermatitisEvaluauononr.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL概述■定義:皮膚或黏膜接觸致敏物后在接觸部位發(fā)生的炎癥反應。分類:原發(fā)刺激性接觸性皮炎irritantdermatitis)變態(tài)反應性接觸性皮炎(allergiccontactdermatitisEvaluauononr.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL病因與發(fā)病機理(Pathogenesisandetiology)病因:動物性:隱翅蟲、松毛蟲、斑蟊蟲植物性:蕁麻、補骨脂、銀杏等化學性:染料、金屬、化妝品、塑料發(fā)病機理:遲發(fā)型變態(tài)反應(Ⅳ型)Delayed-typehypersensitivityEvaluauononr.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL病因與發(fā)病機貍(Pathogenesisandetiology致敏物(半抗原)抗原提呈細胞→完全抗原」+|(APC:皮膚角質蛋白(載體蛋白T細胞活化、增殖致敏T細胞再次接觸致敏物效應T細胞炎癥因子Evaluauononr.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL臨床表現(manifestation)■接觸致敏物后發(fā)病,有一定的潛伏期。起病一般較急,病程較短;皮損好發(fā)于接觸部位,主要是暴露部位;皮疹單一,一般為急性皮疹,境界清;■自覺瘙癢、燒灼感,可有疼痛感;■有自限性。Evaluauononr.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL硝酸刺激強堿刺激Evaluadononly.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL敵敵畏刺激化學物品刺激Evaluationonly.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL隱翅蟲皮炎Evaluadononly.chAsposeslidesforNET4odient