D-Glucuronic-acid-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemED-Glucuronicacid(Standard)Cat.No.:HY-N6612RCASNo.:6556-12-3分?式:C?H??O?分?量:194.14作?靶點:EndogenousMetabolite;Toll-likeReceptor(TLR)作?通路:MetabolicEnzyme/Protease;Immunology/Inflammation儲存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性D-Glucuronicacid(Standard)D-Glucuronicacid的分析標準品。本產(chǎn)品?于研究及分析應(yīng)?。D-Glucuronicacid許多具有抗炎活性蛋?聚糖的主組分，可以促進胚胎發(fā)育和抑制細胞聚集。D-Glucuronicacid代謝為ethylglucuronide(HY-113093)后會激活toll-likereceptor4，從?引起疼痛。D-Glucuronicacid及其衍?物葡萄糖醛酸內(nèi)酯可作為預(yù)防?類健康的肝臟解毒劑，同時其衍?物具有抗腫瘤活性[1][2][3][4][5][6]。REFERENCES[1].TengF,etal.Productionofd-glucuronicacidfrommyo-inositolusingEscherichiacoliwhole-cellbiocatalystoverexpressinganovelmyo-inositoloxygenasefromThermothelomycesthermophile.EnzymeMicrobTechnol.2019Aug;127:70-74.[2].el-NezhawyAO,etal.Design,synthesisandantitumoractivityofnovelD-glucuronicacidderivatives.MedChem.2011Nov;7(6):624-38.[3].LeeJ,etal.EffectofD-GlucuronicAcidandN-acetyl-D-GlucosamineTreatmentduringInVitroMaturationonEmbryonicDevelopmentafterParthenogenesisandSomaticCellNuclearTransferinPigs.Animals(Basel).2021Apr6;11(4):1034.[4].MüllerWE,etal.Purificationandcharacterizationofaspecies-specificaggregationfactorinsponges.ExpCellRes.1973Jul;80(1):95-104.[5].VaithP,etal.OntheroleofD-glucuronicacidintheaggregationofcellsfromthemarinespongeGeodiacydonium.DevCompImmunol.1979Spring;3(2):259-75.[6].LewisSS,etal.Glucuronicacidandtheethanolmetaboliteethyl-glucuronidecausetoll-likereceptor4activationandenhancedpain.BrainBehavImmun.2013May;30:24-32.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-379