E3-Ligase-Ligand-Linker-Conjugates-Chemicals-Modulators-MCE

1、 HYPERLINK https:/www.MedChemE/Targets/E3 Ligase Ligand-Linker Conjugate.html E3 HYPERLINK https:/www.MedChemE/Targets/E3 Ligase Ligand-Linker Conjugate.html HYPERLINK https:/www.MedChemE/Targets/E3 Ligase Ligand-Linker Conjugate.html Ligase HYPERLINK https:/www.MedChemE/Targets/E3 Ligase Ligand-Lin

2、ker Conjugate.html HYPERLINK https:/www.MedChemE/Targets/E3 Ligase Ligand-Linker Conjugate.html Ligand-Linker HYPERLINK https:/www.MedChemE/Targets/E3 Ligase Ligand-Linker Conjugate.html HYPERLINK https:/www.MedChemE/Targets/E3 Ligase Ligand-Linker Conjugate.html ConjugatesE3 Ligase Ligand-Linker Co

3、njugate, which is one part of Proteolysis Targeting Chimeric Molecules (PROTACs), incorporates a ligandfor the E3 ubiquitin ligase and a linker. After linked to the ligand for target protein (such as JQ1 for BRD4 protein, Molibresib forBET protein), those conjugates can be used for constituting PROT

4、ACs that targetprotein for ubiquitination and degradation.Currently, several PROTACs have been found to show good biological activity by specifically targeting BET, estrogen receptor (ER),androgen receptor, etc. MedChemExpress (MCE) offers a wide range of high quality E3 Ligase Ligand-Linker Conjuga

5、tes includingvon Hippel-Lindau (VHL) ligands, MDM2 ligands, Cereblon (CRBN) ligands and cIAP1 ligands conjugating with different linkers(PEGs, Alkyl-Chain, Alkyl/ether, etc.). Its convenient and time-saving for designing and synthesizinga wide variety of novel PROTACs(ARV-825, dBET1,MT-802, etc.), w

6、hich can expand the application of PROTACs in the treatment of cancer, autoimmunity,inflammation and other diseases.www.MedChemE 1 HYPERLINK https:/www.MedChemE/Targets/E3 Ligase Ligand-Linker Conjugate.html E3 HYPERLINK https:/www.MedChemE/Targets/E3 Ligase Ligand-Linker Conjugate.html HYPERLINK ht

7、tps:/www.MedChemE/Targets/E3 Ligase Ligand-Linker Conjugate.html Ligase HYPERLINK https:/www.MedChemE/Targets/E3 Ligase Ligand-Linker Conjugate.html HYPERLINK https:/www.MedChemE/Targets/E3 Ligase Ligand-Linker Conjugate.html Ligand-Linker HYPERLINK https:/www.MedChemE/Targets/E3 Ligase Ligand-Linke

8、r Conjugate.html HYPERLINK https:/www.MedChemE/Targets/E3 Ligase Ligand-Linker Conjugate.html Conjugates HYPERLINK https:/www.MedChemE/Targets/E3 Ligase Ligand-Linker Conjugate.html HYPERLINK https:/www.MedChemE/Targets/E3 Ligase Ligand-Linker Conjugate.html Chemicals HYPERLINK https:/www.MedChemE/E

9、3_ligase_Ligand-Linker_Conjugates_11.html (S,R,S)-AHPC-(C3-PEG)2-C6-Cl HYPERLINK https:/www.MedChemE/E3_ligase_Ligand-Linker_Conjugates_11.html (VHL Ligand-LinkerConjugates 11; E3 ligase Ligand-Linker Conjugates 11) Cat. No.: HY-103608 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-amido-c5-acid.html (S,R

10、,S)-AHPC-amido-C5-acidCat. No.: HY-130798(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a smallmolecule HaloPROTAC that incorporates the(S,R,S)-AHPC based VHL ligand and 2-unit PEGlinker. (S,R,S)-AHPC-(C3-PEG)2-C6-Cl iscapable of inducing the degradation ofGFP-HaloTag7 in cell-based assays.(S,R,S)-AHPC-amido-C5-ac

11、id incorporates a VHLligand for the E3 ubiquitin ligase, and a PROTAClinker. (S,R,S)-AHPC-amido-C5-acid can be used todesign XY028-133 (HY-129180).Purity: 99.89%Clinical Data: No Development ReportedSize: 100 mg, 500 mg, 1 g, 2 gPurity: 97.84%Clinical Data: No Development ReportedSize: 50 mg, 100 mg

12、 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-boc-trans-3-aminocyclobutanol-pip-ch2cooh.html (S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH(VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH) Cat. No.: HY-131168 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c1-br.html (S,R,S)-AHPC-C1-BrCat. No.: HY-1388

13、62(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH(VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH)is a E3 ligase ligand-linker conjugate thatcontains on one end a VHL ligand.(S,R,S)-AHPC-C1-Br is a synthesized E3 ligaseligand-linker conjugate that incorporates the(S,R,S)-AHPC based VHL ligand

14、 and a linkerused in PROTAC technology.Purity: 99.31%Clinical Data: No Development ReportedSize: 10 mg, 25 mg, 50 mg, 100 mgPurity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c1-nh2.html (S,R,S)-AHPC-C1-NH2 HYPERLINK https:/www.MedChemE/s-r-s-a

15、hpc-c1-nh2.html HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c1-nh2-hydrochloride.html (S,R,S)-AHPC-C1-NH2 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c1-nh2-hydrochloride.html HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c1-nh2-hydrochloride.html hydrochlorideCat. No.: HY-138861 Cat. No.: HY-138861A(S,R,S)-AH

16、PC-C1-NH2 is a synthesized E3 ligaseligand-linker conjugate that incorporates the(S,R,S)-AHPC based VHL ligand and a linkerused in PROTAC technology.(S,R,S)-AHPC-C1-NH2 hydrochloride is a synthesizedE3 ligase ligand-linker conjugate thatincorporates the (S,R,S)-AHPC based VHLligand and a linker used

17、in PROTAC technology.Purity: 98%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 25 mg, 50 mg, 100 mgPurity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg HYPERLINK https:/www.MedChemE/e3-ligase-ligand-linker-conjugates-21.html (S,R,S)-AHPC-C10-NH2 HYPERLINK https:/www.MedChemE/e

18、3-ligase-ligand-linker-conjugates-21.html HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c10-nh2-dihydrochloride.html (S,R,S)-AHPC-C10-NH2 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c10-nh2-dihydrochloride.html HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c10-nh2-dihydrochloride.html dihydrochloride(VH032-C10-N

19、H2) Cat. No.: HY-129941 (VH032-C10-NH2 dihydrochloride) Cat. No.: HY-129941A(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is asynthesized E3 ligase ligand-linker conjugatethat incorporates the (S,R,S)-AHPC based VHLligand and a linker used for BET-Targeted PROTAC.(S,R,S)-AHPC-C10-NH2 dihydrochloride(VH032-C1

20、0-NH2 dihydrochloride) is a synthesizedE3 ligase ligand-linker conjugate thatincorporates the (S,R,S)-AHPC based VHL ligandand a linker used for BET-Targeted PROTAC.Purity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mgPurity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg HYPE

21、RLINK https:/www.MedChemE/s-r-s-ahpc-c2-nh2.html (S,R,S)-AHPC-C2-NH2 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c2-nh2.html HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c2-nh2-dihydrochloride.html (S,R,S)-AHPC-C2-NH2 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c2-nh2-dihydrochloride.html HYPERLINK https:/www

22、.MedChemE/s-r-s-ahpc-c2-nh2-dihydrochloride.html dihydrochlorideCat. No.: HY-136163A Cat. No.: HY-136163(S,R,S)-AHPC-C2-NH2 is a synthesized E3 ligaseligand-linker conjugate that incorporates theVH032 based VHL ligand and a linker usedin PROTAC technology.(S,R,S)-AHPC-C2-NH2 dihydrochloride incorpor

23、ates aVHL ligand for the E3 ubiquitin ligase, and aPROTAC linker. (S,R,S)-AHPC-OH can be used in thesynthesis of a series of PROTACs.Purity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mgPurity: 98.85%Clinical Data: No Development ReportedSize: 25 mg2 Tel: 609-228-6898 Fax: 609-228-5909 E

24、mail: salesMedChemE HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c2-peg4-n3.html (S,R,S)-AHPC-C2-PEG4-N3(VH032-C2-PEG4-N3) Cat. No.: HY-130654 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c3-nh2.html (S,R,S)-AHPC-C3-NH2(VH032-C3-NH2) Cat. No.: HY-130711(S,R,S)-AHPC-C2-PEG4-N3 (VH032-C2-PEG4-N3) is asynthesi

25、zed E3 ligase ligand-linker conjugatethat incorporates the (S,R,S)-AHPC based VHLligand and 4-unit PEG linker used in PROTACtechnology.(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is asynthesized E3 ligase ligand-linker conjugatethat incorporates the VH032 based VHL ligand and alinker used in PROTAC technolog

26、y.Purity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mgPurity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c3-nh2-hydrochloride.html (S,R,S)-AHPC-C3-NH2 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c3-nh2-hydrochloride.html HYPERLINK htt

27、ps:/www.MedChemE/s-r-s-ahpc-c3-nh2-hydrochloride.html hydrochloride(VH032-C3-NH2 hydrochloride) Cat. No.: HY-130711B HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c3-nh2-tfa.html (S,R,S)-AHPC-C3-NH2 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c3-nh2-tfa.html HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c3-nh2-t

28、fa.html TFA(VH032-C3-NH2 TFA) Cat. No.: HY-130711A(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) hydrochlorideis a synthesized E3 ligase ligand-linker conjugatethat incorporates the VH032 based VHL ligand and alinker used in PROTAC technology.(S,R,S)-AHPC-C3-NH2 TFA (VH032-C3-NH2 TFA) is asynthesized E3 ligase

29、ligand-linker conjugatethat incorporates the VH032 based VHL ligand and alinker used in PROTAC technology.Purity: 98%Clinical Data: No Development ReportedSize: 5 mgPurity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c4-nh2.html (S,R,S)-AHPC-C4-

30、NH2(VH032-C4-NH2) Cat. No.: HY-114176A HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c4-nh2-dihydrochloride.html (S,R,S)-AHPC-C4-NH2 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c4-nh2-dihydrochloride.html HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c4-nh2-dihydrochloride.html dihydrochloride(VH032-C4-NH2 dihyd

31、rochloride) Cat. No.: HY-114176B(S,R,S)-AHPC-C4-NH2 is a synthesized E3 ligaseligand-linker conjugate that incorporates the(S,R,S)-AHPC based VHL ligand and a linker usedfor EED-Targeted PROTAC.(S,R,S)-AHPC-C4-NH2 dihydrochloride is asynthesized E3 ligase ligand-linker conjugate thatincorporates the

32、 (S,R,S)-AHPC based VHL ligand anda linker used for EED-Targeted PROTAC.Purity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mgPurity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg HYPERLINK https:/www.MedChemE/Protac_linker_5.html (S,R,S)-AHPC-C4-NH2 HYPERLINK https:/www.MedCh

33、emE/Protac_linker_5.html HYPERLINK https:/www.MedChemE/Protac_linker_5.html hydrochloride HYPERLINK https:/www.MedChemE/Protac_linker_5.html (VH032-C4-NH2 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c5-cooh.html (S,R,S)-AHPC-C5-COOHhydrochloride; VHL Ligand-Linker Conjugates 13; ) Cat. No.: HY-114176 (

34、VH032-C5-COOH) Cat. No.: HY-136055(S,R,S)-AHPC-C4-NH2 hydrochloride is a synthesizedE3 ligase ligand-linker conjugate thatincorporates the (S,R,S)-AHPC based VHL ligand anda linker used for EED-Targeted PROTAC.(S,R,S)-AHPC-C5-COOH (VH032-C5-COOH) is asynthesized E3 ligase ligand-linkerconjugate, con

35、tains the VH032 VHL-based ligandand a linker to form PROTACs.Purity: 95.35%Clinical Data: No Development ReportedSize: 10 mM 1 mL, 100 mg, 500 mg, 1 g, 2 gPurity: 98%Clinical Data: No Development ReportedSize: 25 mg, 50 mg, 100 mg HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c5-nh2.html (S,R,S)-AHPC-C5-

36、NH2 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c5-nh2.html HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c6-nh2.html (S,R,S)-AHPC-C6-NH2(VH032-C5-NH2) Cat. No.: HY-136187 (VH032-C6-NH2) Cat. No.: HY-136006B(S,R,S)-AHPC-C5-NH2 (VH032-C5-NH2) is asynthesized E3 ligase ligand-linker conjugatethat incorporates

37、 the VH032 based VHL ligand and alinker used for estrogen-related receptor (ERR)PROTAC degrader.(S,R,S)-AHPC-C6-NH2 (VH032-C6-NH2) is asynthesized E3 ligase ligand-linker conjugate thatincorporates the VH032 based VHL ligand and alinker used in PROTAC technology.Purity: 98%Clinical Data: No Developm

38、ent ReportedSize: 1 mg, 5 mgPurity: 96.64%Clinical Data: No Development ReportedSize: 25 mg, 50 mgwww.MedChemE 3 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c6-nh2-dihydrochloride.html (S,R,S)-AHPC-C6-NH2 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c6-nh2-dihydrochloride.html HYPERLINK https:/www.MedChemE

39、/s-r-s-ahpc-c6-nh2-dihydrochloride.html dihydrochloride(VH032-C6-NH2 dihydrochloride) Cat. No.: HY-136006 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c5-nh2-hydrochloride.html (S,R,S)-AHPC-C6-NH2 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c5-nh2-hydrochloride.html HYPERLINK https:/www.MedChemE/s-r-s-ahpc

40、-c5-nh2-hydrochloride.html hydrochloride(VH032-C6-NH2 hydrochloride) Cat. No.: HY-136006A(S,R,S)-AHPC-C6-NH2 dihydrochloride (VH032-C6-NH2dihydrochloride) is a synthesized E3 ligaseligand-linker conjugate that incorporatesthe VH032 based VHL ligand and a linker usedfor AKT PROTAC degrader.(S,R,S)-AH

41、PC-C6-NH2 hydrochloride (VH032-C6-NH2hydrochloride) is a synthesized E3 ligaseligand-linker conjugate that incorporatesthe VH032 based VHL ligand and a linker used forAKT PROTAC degrader.Purity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mgPurity: 98%Clinical Data: No Development Reporte

42、dSize: 1 mg, 5 mg HYPERLINK https:/www.MedChemE/E3ligase_Ligand-Linker_Conjugates_8.html (S,R,S)-AHPC-C6-PEG3-C4-Cl HYPERLINK https:/www.MedChemE/E3ligase_Ligand-Linker_Conjugates_8.html (VH032-C6-PEG3-C4-Cl; VHLLigand-Linker Conjugates 12; ) Cat. No.: HY-103605 HYPERLINK https:/www.MedChemE/s-r-s-a

43、hpc-c7-amine.html (S,R,S)-AHPC-C7-amine(VH032-C7-amine) Cat. No.: HY-136186(S,R,S)-AHPC-C6-PEG3-C4-Cl (VH032-C6-PEG3-C4-Cl)is a conjugate of ligands for E3 and20-atom-length linker. The connector of linker isHalogen group.(S,R,S)-AHPC-C7-amine (VH032-C7-amine) is asynthesized E3 ligase ligand-linker

44、 conjugatethat incorporates the VH032 based VHL ligand and alinker used for estrogen-related receptor (ERR)PROTAC degrader.Purity: 95.46%Clinical Data: No Development ReportedSize: 100 mg, 500 mg, 1 g, 2 gPurity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg HYPERLINK https:/www.MedChemE

45、/s-r-s-ahpc-c8-nh2.html (S,R,S)-AHPC-C8-NH2(VH032-C8-NH2) Cat. No.: HY-133487B HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c8-nh2-dihydrochloride.html (S,R,S)-AHPC-C8-NH2 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c8-nh2-dihydrochloride.html HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c8-nh2-dihydrochloride

46、.html dihydrochloride(VH032-C8-NH2 dihydrochloride) Cat. No.: HY-133487(S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) is asynthesized E3 ligase ligand-linkerconjugate that incorporates the VH032 basedVHL ligand and a linker used for AKT PROTACdegrader. (S,R,S)-AHPC-C8-NH2 is XF038-164A,example 8, extracted from

47、 patent WO2019173516A1.(S,R,S)-AHPC-C8-NH2 dihydrochloride (VH032-C8-NH2dihydrochloride) is a synthesized E3 ligaseligand-linker conjugate that incorporatesthe VH032 based VHL ligand and a linker usedfor AKT PROTAC degrader.Purity: 95.07%Clinical Data: No Development ReportedSize: 50 mg, 100 mgPurit

48、y: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c8-nh2-hydrochloride.html (S,R,S)-AHPC-C8-NH2 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c8-nh2-hydrochloride.html HYPERLINK https:/www.MedChemE/s-r-s-ahpc-c8-nh2-hydrochloride.html hydrochloride HYPE

49、RLINK https:/www.MedChemE/s-r-s-ahpc-c8-nh2-hydrochloride.html HYPERLINK https:/www.MedChemE/s-r-s-ahpc-co-c9-acid.html (S,R,S)-AHPC-CO-C9-acid(VH032-C8-NH2 hydrochloride) Cat. No.: HY-133487A (VH032-NH-CO-C9-acid) Cat. No.: HY-139345(S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) hydrochlorideis a synthesized E

50、3 ligase ligand-linker conjugatethat incorporates the VH032 based VHL ligand and alinker used in PROTAC technology.(S,R,S)-AHPC-CO-C9-acid is an E3 ligaseligand-linker conjugate that can be connected tothe ligand for protein to form PROTACs.Purity: 98%Clinical Data: No Development ReportedSize: 1 mg

51、, 5 mgPurity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg HYPERLINK https:/www.MedChemE/s-r-s-ahpc-me-c10-br.html (S,R,S)-AHPC-Me-C10-Br HYPERLINK https:/www.MedChemE/s-r-s-ahpc-me-c10-br.html HYPERLINK https:/www.MedChemE/s-r-s-ahpc-me-c10-nh2.html (S,R,S)-AHPC-Me-C10-NH2Cat. No.: HY-

52、130642 Cat. No.: HY-130847(S,R,S)-AHPC-Me-C10-Br is a synthesized E3 ligaseligand-linker conjugate. (S,R,S)-AHPC-Me-C10-Brincorporates a VHL E3 ligase linker and MS432based on the MEK1/2 inhibitor PD0325901.(S,R,S)-AHPC-Me-C10-NH2 is a synthesized E3 ligaseligand-linker conjugate that incorporates t

53、he aVHL ligand and a linker. (S,R,S)-AHPC-Me-C10-NH2can be used in PROTAC MS432 (HY-130602).Purity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mgPurity: 98%Clinical Data: No Development ReportedSize: 50 mg, 100 mg, 500 mg4 Tel: 609-228-6898 Fax: 609-228-5909 Email: salesMedChemE HYPERLIN

54、K https:/www.MedChemE/s-r-s-ahpc-me-c5-cooh.html (S,R,S)-AHPC-Me-C5-COOH HYPERLINK https:/www.MedChemE/s-r-s-ahpc-me-c5-cooh.html HYPERLINK https:/www.MedChemE/s-r-s-ahpc-me-c7-ester.html (S,R,S)-AHPC-Me-C7 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-me-c7-ester.html HYPERLINK https:/www.MedChemE/s-r-s

55、-ahpc-me-c7-ester.html esterCat. No.: HY-130849 Cat. No.: HY-130640(S,R,S)-AHPC-Me-C5-COOH is a synthesized E3 ligaseligand-linker conjugate that incorporates the aVHL ligand and a linker. (S,R,S)-AHPC-Me-C5-COOHcan be used in PROTAC DT2216 (HY-130604).(S,R,S)-AHPC-Me-C7 ester is a E3 ligaseligand-l

56、inker conjugate used to synthesiseBCL-X PROTAC degraders.LPurity: 96.19%Clinical Data: No Development ReportedSize: 50 mg, 100 mgPurity: 98%Clinical Data: No Development ReportedSize: 50 mg, 100 mg HYPERLINK https:/www.MedChemE/s-r-s-ahpc-me-co-ch2-peg3-nh2.html (S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2 HYPER

57、LINK https:/www.MedChemE/s-r-s-ahpc-me-co-ch2-peg3-nh2.html HYPERLINK https:/www.MedChemE/s-r-s-ahpc-me-decanedioic-acid.html (S,R,S)-AHPC-Me-decanedioic HYPERLINK https:/www.MedChemE/s-r-s-ahpc-me-decanedioic-acid.html HYPERLINK https:/www.MedChemE/s-r-s-ahpc-me-decanedioic-acid.html acidCat. No.:

58、HY-131387 Cat. No.: HY-132938(S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2 is a synthesizedE3 ligase ligand-linker conjugate thatincorporates the a VHL ligand and a linker.(S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2 can be used inPROTAC BRD4 Degrader-5 (HY-133737) and PROTAC BRD4Degrader-5-CO-PEG3-N3 (HY-133736).(S,R,S)-AHPC

59、-Me-decanedioic acid is an E3 ligaseligand-linker conjugate that can be used in thesynthesis of PROTACs.Purity: 95.06%Clinical Data: No Development ReportedSize: 25 mg, 100 mgPurity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg HYPERLINK https:/www.MedChemE/s-r-s-ahpc-o-ph-peg1-nh-boc.h

60、tml (S,R,S)-AHPC-O-Ph-PEG1-NH-Boc(VH032-O-Ph-PEG1-NH-Boc) Cat. No.: HY-130638 HYPERLINK https:/www.MedChemE/s-r-s-ahpc-o-ph-peg1-nh2.html (S,R,S)-AHPC-O-Ph-PEG1-NH2(VH032-O-Ph-PEG1-NH2) Cat. No.: HY-130816(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc(VH032-O-Ph-PEG1-NH-Boc) is a synthesized E3ligase ligand-linker c