乳腺癌英文相關(guān)

乳腺癌相關(guān)英文單詞metastaticbreastcancer(MBC)earlymenarchenulliparitylateageatfirstbirthmutationsoftumorsuppressergenesBRCA1andBRCA2radiationexposurecontiguityenvironmentalandlifestylefactorssolitaryunilateralnonmobilenipplechangesprominentskinedemarednesswarmthindurationbonepaindifficultybreathingabdominalpainorenlargementjaundicementalstatuschanges.routinescreeningmammographyasymptomaticwomen.Initialworkuplocalizedlesionsuggestivesymptomsbreastimagingtechniquesultrasoundmagneticresonanceimaging(MRI)BreastbiopsyapalpablemassonphysicalexaminationindicatedforamammographicabnormalitythesizeoftheprimarytumorextentpresenceandextentoflymphnodeinvolvementpresenceorabsenceofdistantmetastasesassistswithtreatmentdecisionsSimplisticallystatedbasementmembraneInvolvementofregionallymphnodesextensivenodalinvolvement

轉(zhuǎn)移性乳腺癌初潮未經(jīng)產(chǎn)頭胎生育年齡大抑癌基因突變?nèi)橄侔┮赘谢?和2射線暴露環(huán)境和生活方式的因素孤立（病灶）單側(cè)皮膚發(fā)紅硬結(jié)骨痛呼吸困難黃疸精神狀態(tài)改變無(wú)癥狀的患者初始的檢查局限的病灶具有提示意義的癥狀乳腺成像技術(shù)超聲活檢體格檢查可觸及腫塊（預(yù)示）乳腺異常原發(fā)灶大小是否存在淋巴結(jié)轉(zhuǎn)移及數(shù)目是否存在遠(yuǎn)處轉(zhuǎn)移協(xié)助治療方案決策簡(jiǎn)單來(lái)說(shuō)基底膜區(qū)域淋巴結(jié)受侵淋巴結(jié)廣泛受侵fixedtothechestinflammatorybreastcancerrapidlyprogressivepreinvasiveadenocarcinomasductallobularmaximizequantityandqualityoflifeaxillarylymphnodestheriskforbreastcancerrecurrencediseasecharacteristicsprovideprognosticinformationhistologicsubtypenuclearorhistologicgradelymphaticandvascularinvasionproliferationindicesTheestrogenreceptor(ER)progesteronereceptor(PR)predictresponsetohormonetherapyHER2/neu(HER2)overexpressiontransmissionofgrowthsignalsthatcontrolaspectsofnormalcellgrowthanddivisionincreasedtumoraggressivenessratesofrecurrencemortalityfavorableprognosticfeaturescureprolongsurvivalrapidlyevolvingthemostpromisinginterventionsintheprimaryliteraturecombinationregimenappropriatereferencesshouldbeconsulted.Breast-conservingtherapy(BCT)modifiedradicalmastectomycosmeticallysuperiorresultslumpectomyradiationtherapy(RT)preventlocalrecurrence.ReddeninganderythemaofthebreasttissueSimpleortotalmastectomydissectionofunderlyingmuscleoraxillarynodescarcinomainsitu

進(jìn)展迅速轉(zhuǎn)移前腺癌延長(zhǎng)生存期，提高生活質(zhì)量腋窩淋巴結(jié)乳腺癌復(fù)發(fā)的風(fēng)險(xiǎn)疾病特點(diǎn)提供預(yù)后信息組織學(xué)亞型核分級(jí)及組織分級(jí)增殖指數(shù)雌激素受體孕激素受體預(yù)測(cè)對(duì)激素治療的反應(yīng)HER2過(guò)表達(dá)控制正常細(xì)胞生長(zhǎng)分裂的生長(zhǎng)信號(hào)的傳遞復(fù)發(fā)率死亡率好的預(yù)后因素治愈延長(zhǎng)生存快速發(fā)展在原始文獻(xiàn)中聯(lián)合治療方案查找適宜的參考文獻(xiàn)保乳術(shù)改良根治術(shù)效果更美觀乳腺腫瘤切除術(shù)放療預(yù)防局部復(fù)發(fā)乳腺組織紅腫簡(jiǎn)單或全乳切除術(shù)切除下方肌肉及腋窩淋巴結(jié)原位癌LymphaticmappingwithsentinellymphnodebiopsyinvasivephasesLocal-RegionalTherapypreferabletosubsequentshrinkageminorcomplicationsdefinitivelocaltherapyreflectthetrendtowardtheuseofchemotherapymenopausalstatusdecision-supporttoolsdistantrecurrenceatatimeoflowtumorburdenemergenceofdrug-resistanttumorcellclonesSelectedAdjuvantChemotherapyRegimensAnthracycline-containingregimensdoxorubicinepirubicintaxanesdocetaxelpaclitaxelDoseintensityDosedensityDose-denseregimensserotonin-antagonistsubstanceP/neurokinin1–antagonistcolony-stimulatingfactorsADJUVANTBIOLOGICTHERAPYadjuvanttrastuzumaboptimalconcurrentchemotherapyTamoxifentoremifeneoophorectomyovarianirradiationluteinizinghormone–releasing(LHRH)agonistsaromataseinhibitorsadjuvanthormonaltherapyofchoicepremenopausalwomenestrogenicantiestrogenicpropertiesestrogenwithdrawalhotflashes

前哨淋巴結(jié)活檢了解淋巴結(jié)定位及受侵局部治療更優(yōu)于治療后縮小傾向于化療月經(jīng)狀態(tài)遠(yuǎn)處轉(zhuǎn)移腫瘤負(fù)荷小多柔比星紫杉類紫杉醇劑量密集方案5-羥色胺拮抗劑P物質(zhì)/神經(jīng)激肽1拮抗劑集落刺激因子輔助生物治療他莫昔芬托瑞米芬卵巢放療促黃體生成激素釋放激素（LHRH）激動(dòng)劑芳香化酶抑制劑最佳輔助內(nèi)分泌治療未絕經(jīng)女性雌激素的抗雌激素的特點(diǎn)雌激素撤退潮熱vaginalbleedingdecreaseinfrequencyandintensityovertimehipradiusspinefracturesstrokepulmonaryembolismdeepveinthrombosisendometrialcancerovarianablationwithLHRHagonistsgoserelinanastrozoleletrozoleexemestanebonelossosteoporosismyalgiaarthralgiarenderinginoperabletumorsresectableincreasingtherateofBCTextendsurvivalThechoiceoftherapyhormonereceptopositivesofttissuepleuraviscerasequentiallytreatedwithendocrinetherapyceasetorespondcirculatingandtargetorganestrogensblockingperipheralconversionfromanandrogenicprecursorprototypeaminoglutethimidelowerincidenceofthromboemboliceventsFulvestrantprogressedontamoxifenMedicalcastrationreservedforthird-linetherapyweightgainfluidretentionleuprolidetriptorelinThechoiceoftreatmentdependsonindividualtimetoprogression

陰道出血頻率和強(qiáng)度隨著時(shí)間推移而下降髖關(guān)節(jié)半徑脊柱骨折中風(fēng)肺栓塞深靜脈血栓子宮內(nèi)膜癌應(yīng)用LHRH激動(dòng)劑使卵巢去勢(shì)戈舍瑞林阿那曲唑來(lái)曲唑依西美坦骨量丟失骨質(zhì)疏松肌痛關(guān)節(jié)痛使不可切除腫瘤降級(jí)為可切除保乳率提高延長(zhǎng)生存治療方案的選擇轉(zhuǎn)移灶激素受體陽(yáng)性軟組織胸膜腹腔逐一內(nèi)分泌治療不再獲益循環(huán)中及靶器官的雌激素抑制外周雄激素轉(zhuǎn)化原型氨魯米特氟維司群藥物去勢(shì)體重增加液體潴留亮丙瑞林曲普瑞林至進(jìn)展時(shí)間sequentialsingleagentsrecommendedoverobjectiveresponsesThemediandurationofresponseunequivocalevidenceofprogressivediseasecardiotoxicityunacceptablyhighdoublet/tripletcombinationsTrastuzumabanoraltyrosinekinaseinhibitorepidermalgrowthfactorreceptorrashdiarrheapainfulbonemetastasesbrainandspi