GB/T 44707-2024化學(xué)品強(qiáng)化快速生物降解性試驗(yàn)

ICS

13.300

CCS

A80

中華人民共和國國家標(biāo)準(zhǔn)

GB/T44707—2024

化學(xué)品強(qiáng)化快速生物降解性試驗(yàn)

Chemicals—Enhancedreadybiodegradabilitytest

2024-10-26發(fā)布2025-05-01實(shí)施

國家市場監(jiān)督管理總局發(fā)布

國家標(biāo)準(zhǔn)化管理委員會

GB/T44707—2024

目次

前言

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Ⅲ

引言

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Ⅳ

1

范圍

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2

規(guī)范性引用文件

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3

術(shù)語和定義

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4

方法概述

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4.1

原理

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4.2

方法選擇

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5

受試物信息

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參比物

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7

試驗(yàn)準(zhǔn)備

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7.1

儀器設(shè)備

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7.2

試驗(yàn)用水和培養(yǎng)基

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7.3

接種物

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8

試驗(yàn)程序

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8.1

強(qiáng)化條件

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8.2

受試物的添加

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8.3

試驗(yàn)操作

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9

質(zhì)量保證與質(zhì)量控制

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10

數(shù)據(jù)

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11

結(jié)果報告

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5

參考文獻(xiàn)

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Ⅰ

GB/T44707—2024

前言

本文件按照GB/T1.1—2020《標(biāo)準(zhǔn)化工作導(dǎo)則第1部分：標(biāo)準(zhǔn)化文件的結(jié)構(gòu)和起草規(guī)則》的規(guī)

定起草。

本文件與GB/T27850《化學(xué)品快速生物降解性通則》、GB/T21801《化學(xué)品快速生物降解

性呼吸計(jì)量法試驗(yàn)》、GB/T21802《化學(xué)品快速生物降解性改進(jìn)的MITI試驗(yàn)（Ⅰ）》、GB/T21803

《化學(xué)品快速生物降解性DOC消減試驗(yàn)》、GB/T21831《化學(xué)品快速生物降解性：密閉瓶法試

驗(yàn)》、GB/T21856《化學(xué)品快速生物降解性二氧化碳產(chǎn)生試驗(yàn)》和GB/T21857《化學(xué)品快速

生物降解性改進(jìn)的OECD篩選試驗(yàn)》配套使用。

請注意本文件的某些內(nèi)容可能涉及專利。本文件的發(fā)布機(jī)構(gòu)不承擔(dān)識別專利的責(zé)任。

本文件由全國危險化學(xué)品管理標(biāo)準(zhǔn)化技術(shù)委員會（SAC/TC251）提出并歸口。

本文件起草單位：廣東省科學(xué)院微生物研究所（廣東省微生物分析檢測中心）、生態(tài)環(huán)境部固體廢

物與化學(xué)品管理技術(shù)中心、中檢科?。ㄌ旖颍z驗(yàn)檢測有限責(zé)任公司、路博潤管理（上海）有限公司、

上海市檢測中心、生態(tài)環(huán)境部南京環(huán)境科學(xué)研究所、上海化工院檢測有限公司、沈陽沈化院測試技術(shù)有

限公司、中國合格評定國家認(rèn)可中心、萬華化學(xué)集團(tuán)股份有限公司、福斯?jié)櫥停ㄖ袊┯邢薰?、?/p>

特科技有限公司。

本文件主要起草人：許玫英、梅承芳、吳孝槐、鄧桂榮、劉純新、曾國驅(qū)、羅鳳娟、周麗麗、

滕曉明、邢維龍、舒耀皋、戎志毅、葉芷君、楊雪菲、周彬彬、孫帥、喬建成。

Ⅲ

GB/T44707—2024

引言

當(dāng)化合物在快速生物降解性試驗(yàn)中表現(xiàn)為不具有快速生物降解性時，需要進(jìn)一步開展更多的篩選性

降解試驗(yàn)，如強(qiáng)化快速生物降解性試驗(yàn)、固有生物降解性試驗(yàn)等，以識別是否具有潛在的持久性。推薦

采用強(qiáng)化快速生物降解性試驗(yàn)評估持久性，其方法選擇更廣、優(yōu)化條件更全面。

本文件與快速生物降解性通則（GB/T27850）及任一快速生物降解性試驗(yàn)方法（GB/T21801、

GB/T21802、GB/T21803、GB/T21831、GB/T21856、GB/T21857和OECD化學(xué)品測試導(dǎo)則

No.310）聯(lián)合使用，將所選用的快速生物降解性試驗(yàn)標(biāo)準(zhǔn)作為基礎(chǔ)方法，通過對一個或多個試驗(yàn)條件

進(jìn)行強(qiáng)化開展測試。除本文件描述的內(nèi)容之外，其他試驗(yàn)內(nèi)容和要求見所選用的方法標(biāo)準(zhǔn)。

如采用本文件通過預(yù)暴露接種物或增加接種物濃度開展測試并將獲得的數(shù)據(jù)用于監(jiān)管時，需考慮試

驗(yàn)結(jié)果是否充分且有效。

Ⅳ

GB/T44707—2024

化學(xué)品強(qiáng)化快速生物降解性試驗(yàn)

1范圍

本文件描述了化學(xué)品強(qiáng)化快速生物降解性試驗(yàn)的方法概述、受試物信息、參比物、試驗(yàn)準(zhǔn)備、試驗(yàn)

程序、質(zhì)量保證與質(zhì)量控制、數(shù)據(jù)、結(jié)果報告。

本文件適用于化學(xué)品的強(qiáng)化快速生物降解性試驗(yàn)。

2規(guī)范性引用文件

下列文件中的內(nèi)容通過文中的規(guī)范性引用而構(gòu)成本文件必不可少的條款。其中，注日期的引用文

件，僅該日期對應(yīng)的版本適用于本文件；不注日期的引用文件，其最新版本（包括所有的修改單）適用

于本文件。

GB/T21801化學(xué)品快速生物降解性呼吸計(jì)量法試驗(yàn)

GB/T21802化學(xué)品快速生物降解性改進(jìn)的MITI試驗(yàn)（Ⅰ）

GB/T21803化學(xué)品快速生物降解性DOC消減試驗(yàn)

GB/T21831化學(xué)品快速生物降解性：密閉瓶法試驗(yàn)

GB/T21856化學(xué)品快速生物降解性二氧化碳產(chǎn)生試驗(yàn)

GB/T21857化學(xué)品快速生物降解性改進(jìn)的OECD篩選試驗(yàn)

GB/T27850化學(xué)品快速生物降解性通則

OECD化學(xué)品測試導(dǎo)則No.310

快速生物降解性?密閉瓶二氧化碳法（頂