時(shí)間常數(shù)實(shí)用學(xué)習(xí)教案

1、時(shí)間常數(shù)時(shí)間常數(shù)(sh jin chn sh)實(shí)用實(shí)用第一頁，共22頁。第1頁/共22頁第二頁，共22頁。第2頁/共22頁第三頁，共22頁。第3頁/共22頁第四頁，共22頁。第4頁/共22頁第五頁，共22頁。RC第5頁/共22頁第六頁，共22頁。第6頁/共22頁第七頁，共22頁。第7頁/共22頁第八頁，共22頁。PEFREELV吸氣吸氣(x q)呼氣呼氣PIFRVT第8頁/共22頁第九頁，共22頁。Brunner JX, Laubscher TP, Banner MJ, et al. Simple method to measure total expiratory time constant

2、 based on the passive expiratory flow-volume curve. Critical Care Med 1995; 23(6):1117-1122流量(liling)(L/min)容積(rngj)(L)0VtPEFR第9頁/共22頁第十頁，共22頁。Brunner JX, Laubscher TP, Banner MJ, et al. Simple method to measure total expiratory time constant based on the passive expiratory flow-volume curve. Critic

3、al Care Med 1995; 23(6):1117-1122流量(liling)(L/min)容積(rngj)(L)0VtPEFRTauE = Vt / PEFR第10頁/共22頁第十一頁，共22頁。第11頁/共22頁第十二頁，共22頁。第12頁/共22頁第十三頁，共22頁。Brunner JX, Laubscher TP, Banner MJ, et al. Simple method to measure total expiratory time constant based on the passive expiratory flow-volume curve. Critical

4、 Care Med 1995; 23(6):1117-1122模擬(mn)肺y = 0.975x + 0.169r2 = 0.974動(dòng)物(dngw)試驗(yàn)(犬)y = 1.033x + 0.038r2 = 0.969第13頁/共22頁第十四頁，共22頁。Brunner JX, Laubscher TP, Banner MJ, et al. Simple method to measure total expiratory time constant based on the passive expiratory flow-volume curve. Critical Care Med 1995;

5、 23(6):1117-1122第14頁/共22頁第十五頁，共22頁。Lourens MS, van den Berg B, Aerts JGJV, et al. Expiratory time constants in mechanically ventilated patients with and without COPD. Intensive Care Med 2000; 26: 1612-1618第15頁/共22頁第十六頁，共22頁。Lourens MS, van den Berg B, Aerts JGJV, et al. Expiratory time constants in

6、mechanically ventilated patients with and without COPD. Intensive Care Med 2000; 26: 1612-1618RCfv100 = Vt / (V100, exp Vend, ex)RCfv75 = 0.75 x Vt / (V75, exp Vend, ex)RCfv50 = 0.50 x Vt / (V50, exp Vend, ex)RCfv25 = 0.25 x Vt / (V25, exp Vend, ex)第16頁/共22頁第十七頁，共22頁。Lourens MS, van den Berg B, Aert

7、s JGJV, et al. Expiratory time constants in mechanically ventilated patients with and without COPD. Intensive Care Med 2000; 26: 1612-1618重度COPD中度COPD其他病因RCint2.88 1.611.02 0.400.65 0.28RCfvp0.75 0.200.70 0.190.60 0.10RCfv1000.85 0.180.79 0.220.63 0.12RCfv752.84 1.531.05 0.320.72 0.18RCfv503.42 1.61

8、 1.25 0.440.84 0.39RCfv254.20 1.991.47 0.571.06 0.63第17頁/共22頁第十八頁，共22頁。Lourens MS, van den Berg B, Aerts JGJV, et al. Expiratory time constants in mechanically ventilated patients with and without COPD. Intensive Care Med 2000; 26: 1612-1618第18頁/共22頁第十九頁，共22頁。Lourens MS, van den Berg B, Aerts JGJV, et al. Expiratory time constants in mechanically ventilated patients with and without CO