GSK-3-Inhibitors-Modulators-MCE

1、 HYPERLINK https:/www.MedChemE/Targets/GSK-3.html GSK-3Glycogen synthase kinase-3; Glycogen synthase kinase 3Glycogen synthase kinase 3 (GSK-3) is a multifunctional serine/threonine kinase consisting of two isoforms, alpha and beta. It is ahighly conserved negative regulator of receptor tyrosine kin

2、ase, cytokine, and Wnt signaling pathways. Stimulation of thesepathways inhibits GSK-3 to modulate diverse downstream effectors that include transcription factors, nutrient sensors, glycogensynthesis, mitochondrial function, circadian rhythm, and cell fate. GSK-3 also regulates alternative splicing

3、in response to T-cellreceptor activation, and recent phosphoproteomic studies have revealed that multiple splicing factors and regulators of RNAbiosynthesis are phosphorylated in a GSK-3-dependent manner.The malfunction or aberrant activity of GSK-3 leads to several of disorders, such as Alzheimers

4、disease (AD) and otherneurodegenerative pathologies, and other type of diseases as diabetes, cardiovascular disorders and cancer. GSK-3 is also relatedto innate immune response against pathogens, which makes GSK-3 an excellent target for therapeutic intervention.www.MedChemE 12 Tel: 609-228-6898 Fax

5、: 609-228-5909 Email: salesMedChemE HYPERLINK https:/www.MedChemE/Targets/GSK-3.html GSK-3 HYPERLINK https:/www.MedChemE/Targets/GSK-3.html HYPERLINK https:/www.MedChemE/Targets/GSK-3.html Inhibitors HYPERLINK https:/www.MedChemE/e-z-bio-acetoxime.html (E/Z)-BIO-acetoxime(GSK-3 Inhibitor X) Cat. No.

6、: HY-114903 HYPERLINK https:/www.MedChemE/e-z-gsk-3-inhibitor-1.html (E/Z)-GSK-3 HYPERLINK https:/www.MedChemE/e-z-gsk-3-inhibitor-1.html HYPERLINK https:/www.MedChemE/e-z-gsk-3-inhibitor-1.html inhibitor HYPERLINK https:/www.MedChemE/e-z-gsk-3-inhibitor-1.html HYPERLINK https:/www.MedChemE/e-z-gsk-

7、3-inhibitor-1.html 1Cat. No.: HY-126144A(E/Z)-BIO-acetoxime (GSK-3 Inhibitor X) is apotent and selective GSK-3/ inhibitor, with anIC of 10 nM. (E/Z)-BIO-acetoxime shows more than50200-flod selectivity over CDK5/p25, CDK2/cyclin Aand CDK1/cyclin B (IC =2.4, 4.3, 63 M).50Purity: 98%Clinical Data: No D

8、evelopment ReportedSize: 5 mg, 10 mg(E/Z)-GSK-3 inhibitor 1 is a racemic compound of(E)-GSK-3 inhibitor 1 and (Z)-GSK-3 inhibitor 1isomers. GSK-3 inhibitor 1 (compound 3a) is aglycogen synthase kinase 3 (GSK-3) inhibitor anddemonstrates high antidiabetic efficacy, with anIC of 4.9 nM.50Purity: 98.56

9、%Clinical Data: No Development ReportedSize: 10 mM 1 mL, 5 mg, 10 mg, 50 mg HYPERLINK https:/www.MedChemE/brd3731.html (R)-BRD3731 HYPERLINK https:/www.MedChemE/brd3731.html HYPERLINK https:/www.MedChemE/rac-brd0705.html (Rac)-BRD0705Cat. No.: HY-124607 Cat. No.: HY-116830A(R)-BRD3731 is a GSK3 inhi

10、bitor extracted frompatent US20160375006A1, compound example 273, hasIC50s of 1.05 and 6.7 M for GSK3 and GSK3,respectively.Purity: 98.22%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 50 mg, 100 mg(Rac)-BRD0705 is a less active racemate ofBRD0705. BRD0705 is a potent, paralog selectiveand

11、 orally active GSK3 inhibitor with an IC of5066 nM and a K of 4.8 M. BRD0705 displaysdincreased selectivity for GSK3 (8-fold) versusGSK3 (IC of 515 nM).50Purity: 98%Clinical Data: No Development ReportedSize: 10 mM 1 mL, 5 mg, 10 mg, 50 mg, 100 mg HYPERLINK https:/www.MedChemE/1-azakenpaullone.html

12、1-Azakenpaullone(1-Akp) Cat. No.: HY-59090 HYPERLINK https:/www.MedChemE/2b-sp.html 2B-(SP)Cat. No.: HY-P11141-Azakenpaullone (1-Akp) is a highly selective andATP-competitive inhibitor of glycogen synthasekinase-3 (GSK-3), with an IC value of 18 nM.502B-(SP) is a eIF2B-based substrate for glycogensy

13、nthase kinase-3 (GSK-3). 2B-(SP) is readilyphosphorylated by both the and isoforms ofGSK-3.Purity: 98.20%Clinical Data: No Development ReportedSize: 10 mM 1 mL, 2 mg, 5 mg, 10 mgPurity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg HYPERLINK https:/www.MedChemE/2b-sp-tfa.html 2B-(SP) HYP

14、ERLINK https:/www.MedChemE/2b-sp-tfa.html HYPERLINK https:/www.MedChemE/2b-sp-tfa.html (TFA) HYPERLINK https:/www.MedChemE/2b-sp-tfa.html HYPERLINK https:/www.MedChemE/3-methylthienyl-carbonyl-jnj-7706621.html 3-Methylthienyl-carbonyl-JNJ-7706621Cat. No.: HY-P1114A Cat. No.: HY-1416852B-(SP) TFA is

15、a eIF2B-based substrate forglycogen synthase kinase-3 (GSK-3). 2B-(SP) TFAis readily phosphorylated by both the and isoforms of GSK-3.3-Methylthienyl-carbonyl-JNJ-7706621 is a potentand selective inhibitor of cyclin-dependent kinase(CDK), with IC s of 6.4 nM and 2 nM for50CDK1/cyclinB and CDK2/cycli

16、nA, respectively.Purity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mgPurity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg HYPERLINK https:/www.MedChemE/3f8.html 3F8 HYPERLINK https:/www.MedChemE/3f8.html HYPERLINK https:/www.MedChemE/5-iodo-indirubin-3-monoxime.html 5-Iodo-

17、indirubin-3-monoximeCat. No.: HY-107530 Cat. No.: HY-1119303F8 is a potent and selective GSK-3 inhibitorthat could be useful as new reagent and potentialtherapeutic candidate for GSK3 related diseases.5-Iodo-indirubin-3-monoxime is a potent GSK-3,CDK5/P25 and CDK1/cyclin B inhibitor, competingwith A

18、TP for binding to the catalytic site of thekinase, with IC s of 9, 20 and 25 nM,50respectively.Purity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mgPurity: 99.50%Clinical Data: No Development ReportedSize: 10 mM 1 mL, 5 mg, 10 mg, 50 mg, 100 mgwww.MedChemE 3 HYPERLINK https:/www.MedChemE

19、/7bio.html 7BIO(7-Bromoindirubin-3-Oxime) Cat. No.: HY-121035 HYPERLINK https:/www.MedChemE/9-ing-41.html 9-ING-41Cat. No.: HY-1139147BIO (7-Bromoindirubin-3-Oxime) is the derivate ofindirubin. 7BIO (7-Bromoindirubin-3-Oxime) hasinhibitory effects against cyclin-dependentkinase-5 (CDK5) and glycogen

20、 synthase kinase-3(GSK3).9-ING-41 is a maleimide-based ATP-competitive andselective glycogen synthase kinase-3 (GSK-3)inhibitor with an IC of 0.71 M. 9-ING-4150significantly leads to cell cycle arrest,autophagy and apoptosis in cancer cells.Purity: 98.0%Clinical Data: No Development ReportedSize: 5

21、mg, 10 mg, 25 mg, 50 mg, 100 mgPurity: 99.32%Clinical Data: Phase 2Size: 10 mM 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg HYPERLINK https:/www.MedChemE/a-1070722.html A HYPERLINK https:/www.MedChemE/a-1070722.html HYPERLINK https:/www.MedChemE/a-1070722.html 1070722Cat. No.: HY-107531 HYPERLINK https:/

22、www.MedChemE/aloisine-a.html Aloisine HYPERLINK https:/www.MedChemE/aloisine-a.html HYPERLINK https:/www.MedChemE/aloisine-a.html A(RP107) Cat. No.: HY-112363A 1070722 is a potent and selective glycogensynthase kinase 3 (GSK-3) inhibitor, with a K ofi0.6 nM for both GSK-3 and GSK-3.Purity: 99.48%Cli

23、nical Data: No Development ReportedSize: 10 mM 1 mL, 10 mg, 50 mgAloisine A (RP107) is a a potent cyclin-dependentkinase (CDK) inhibitor with IC s of 0.15 M, 0.1250M, 0.4 M, 0.16 M for CDK1/cyclin B, CDK2/cyclinA, CDK2/cyclin E, CDK5/p35, respectively. AloisineA ininhibits GSK-3 (IC =0.5 M) and GSK-

24、350(IC =1.5 M).50Purity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg HYPERLINK https:/www.MedChemE/alsterpaullone.html Alsterpaullone(9-Nitropaullone; NSC 705701) Cat. No.: HY-108359 HYPERLINK https:/www.MedChemE/AR-A014418.html AR-A014418(AR 0133418; GSK 3 inhibitor VIII; AR 014418) C

25、at. No.: HY-10512Alsterpaullone (9-Nitropaullone) is a potent CDKinhibitor, with IC s of 35 nM, 15 nM, 200 nM and5040 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclinE and CDK5/p35, respectively.AR-A014418 is a potent, selective andATP-competitive GSK3 inhibitor (IC =104 nM;50K=38 nM).iPurity: 98.38

26、%Clinical Data: No Development ReportedSize: 5 mg, 10 mgPurity: 99.49%Clinical Data: No Development ReportedSize: 10 mM 1 mL, 5 mg, 10 mg, 50 mg, 100 mg HYPERLINK https:/www.MedChemE/ar-a014418-d3.html AR-A014418-d3 HYPERLINK https:/www.MedChemE/ar-a014418-d3.html HYPERLINK https:/www.MedChemE/arn25

27、068.html ARN25068(AR 0133418-d3; GSK 3 inhibitor VIII-d3; AR 014418-d3) Cat. No.: HY-10512SCat. No.: HY-144290AR-A014418-d3 (AR 0133418-d3) is the deuteriumlabeled AR-A014418. AR-A014418 is a potent,selective, and ATP-competitive GSK3 inhibitor(IC =104 nM; K=38 nM).50 iARN25068 is a sub-micromolar i

28、nhibitor of thethree protein kinases, GSK-3, FYN and DYRK1Ato tackle tau hyperphosphorylation.Purity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mgPurity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg HYPERLINK https:/www.MedChemE/AZD1080.html AZD1080 HYPERLINK https:/www.Med

29、ChemE/AZD1080.html HYPERLINK https:/www.MedChemE/AZD2858.html AZD2858Cat. No.: HY-13862 Cat. No.: HY-15761AZD1080 is a potent and selective GSK3 inhibitor.AZD1080 inhibits recombinant human GSK3 andGSK3 with pKi (IC50) of 8.2 (6.9 nM) and 7.5 (31nM), respectively.AZD2858 is a potent, orally active G

30、SK-3inhibitor, with IC s of 0.9 and 5 nM for50 GSK-3and GSK-3, respectively, used in the research offracture healing.Purity: 99.46%Clinical Data: No Development ReportedSize: 10 mM 1 mL, 5 mg, 10 mg, 50 mg, 100 mgPurity: 99.42%Clinical Data: No Development ReportedSize: 10 mM 1 mL, 10 mg, 50 mg4 Tel

31、: 609-228-6898 Fax: 609-228-5909 Email: salesMedChemE HYPERLINK https:/www.MedChemE/Bikinin.html Bikinin(Abrasin) Cat. No.: HY-12524 HYPERLINK https:/www.MedChemE/BIO-acetoxime.html BIO-acetoxime(BIA) Cat. No.: HY-15356Bikinin is a non-steroidal, ATP-competitiveinhibitor of plant GSK-3/Shaggy-like k

32、inases andactivates BR (brassinosteroids) signaling.BIO-acetoxime (BIA) is a potent and selectiveGSK-3 inhibitor, with IC s of both 10 nM for50GSK-3/. BIO-acetoxime has anticonvulsant andanti-infection activity.Purity: 99.94%Clinical Data: No Development ReportedSize: 10 mM 1 mL, 5 mg, 10 mg, 50 mg,

33、 100 mgPurity: 98.0%Clinical Data: No Development ReportedSize: 10 mM 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg HYPERLINK https:/www.MedChemE/bip-135.html BIP-135 HYPERLINK https:/www.MedChemE/bip-135.html HYPERLINK https:/www.MedChemE/brd0209.html BRD0209Cat. No.: HY-111055 Cat. No.: HY-117822BIP-135

34、 is a potent and selective ATP-competitiveGSK-3 inhibitor, with IC s of 16 nM and 21 nM50for GSK-3 and GSK-3, respectively. BIP 135exhibits neuroprotective effect.BRD0209 is a potent, selective and dual inhibitorof GSK3/ inhibitor (GSK3 IC = 19 nM; GSK350IC = 5 nM). BRD0209 is also a reversible50ATP

35、-competitive inhibitor with fast-off kinetics(K = 4.2 nM, respectively).iPurity: 98.31%Clinical Data: No Development ReportedSize: 1 mg, 5 mg, 10 mgPurity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg HYPERLINK https:/www.MedChemE/brd0705.html BRD0705 HYPERLINK https:/www.MedChemE/brd07

36、05.html HYPERLINK https:/www.MedChemE/s-brd3731.html BRD3731Cat. No.: HY-116830 Cat. No.: HY-124607BBRD0705 is a potent, paralog selective and orallyactive GSK3 inhibitor with an IC of 66 nM and50a K of 4.8 M. BRD0705 displays increaseddselectivity for GSK3 (8-fold) versus GSK3 (IC50of 515 nM). BRD0

37、705 can be used for acute myeloidleukemia (AML) research.BRD3731 is a selective GSK3 inhibitor, withIC s of 15 nM and 215 nM for GSK3 and GSK3,50respectively. BRD3731 is potentail for theresearch of post-traumatic stress disorder (PTSD),psychiatric disorder, diabetes, andneurodegenerative disorders.

38、Purity: 98.41%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 50 mg, 100 mgPurity: 98.02%Clinical Data: No Development ReportedSize: 10 mM 1 mL, 5 mg, 10 mg, 50 mg, 100 mg HYPERLINK https:/www.MedChemE/brd5648.html BRD5648 HYPERLINK https:/www.MedChemE/brd5648.html HYPERLINK https:/www.MedC

39、hemE/CHIR-98014.html CHIR-98014(R)-BRD0705) Cat. No.: HY-116830BCat. No.: HY-13076BRD5648 (R)-BRD0705) is a negative control ofBRD0705. BRD0705 is a potent, paralog selectiveand orally active GSK3 inhibitor with an IC of5066 nM and a K of 4.8 M. BRD0705 displaysdincreased selectivity for GSK3 (8-fol

40、d) versusGSK3 (IC of 515 nM).50Purity: 97.07%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 50 mg, 100 mgCHIR-98014 is a potent, cell-permeable GSK-3inhibitor with IC s of 0.65 and 0.58 nM for50GSK-3 and GSK-3, respectively; it shows lesspotent activities against cdc2 and erk2.Purity: 98.0

41、%Clinical Data: No Development ReportedSize: 10 mM 1 mL, 5 mg, 10 mg, 50 mg HYPERLINK https:/www.MedChemE/chir-98023.html CHIR-98023 HYPERLINK https:/www.MedChemE/chir-98023.html HYPERLINK https:/www.MedChemE/CP21R7.html CP21R7Cat. No.: HY-126125(CP21) Cat. No.: HY-100207CHIR-98023 is a potent, sele

42、ctive and reversibleinhibitor of GSK3, with IC s of 10 nM and 6.7 nM50for GSK3 and GSK3, respectively. CHIR-98023can improve insulin action and glucose metabolism.CP21R7 is potent GSK-3 inhibitor, with an IC50of 1.8 nM; CP21R7 also shows inhibitory activitiyagainst PKC, with an IC of 1900 nM.50Purit

43、y: 98%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 50 mg, 100 mgPurity: 99.51%Clinical Data: No Development ReportedSize: 10 mM 1 mL, 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mgwww.MedChemE 5 HYPERLINK https:/www.MedChemE/Cromolyn-sodium.html Cromolyn HYPERLINK https:/www.MedChemE/Cromolyn-s

44、odium.html HYPERLINK https:/www.MedChemE/Cromolyn-sodium.html sodium(Disodium Cromoglycate; FPL-670) Cat. No.: HY-B0320A HYPERLINK https:/www.MedChemE/cromolyn-d5-sodium.html Cromolyn-d5 HYPERLINK https:/www.MedChemE/cromolyn-d5-sodium.html HYPERLINK https:/www.MedChemE/cromolyn-d5-sodium.html sodiu

45、m(Disodium Cromoglycate-d5; FPL-670-d5) Cat. No.: HY-B0320ASCromolyn sodium (Disodium Cromoglycate; FPL-670)is an antiallergic drug. Cromolyn sodium is aGSK-3 inhibitor with an IC of 2.0 M.50Cromolyn-d5 sodium (Disodium Cromoglycate-d5) isthe deuterium labeled Cromolyn sodium. Cromolynsodium (Disodi

46、um Cromoglycate; FPL-670) is anantiallergic drug. Cromolyn sodium is a GSK-3inhibitor with an IC of 2.0 M.50Purity: 99.10%Clinical Data: LaunchedSize: 10 mM 1 mL, 500 mg, 1 g, 5 gPurity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg HYPERLINK https:/www.MedChemE/cu-ii-gtsm.html Cu(II)GTS

47、M HYPERLINK https:/www.MedChemE/cu-ii-gtsm.html HYPERLINK https:/www.MedChemE/eht-5372.html EHT HYPERLINK https:/www.MedChemE/eht-5372.html HYPERLINK https:/www.MedChemE/eht-5372.html 5372Cat. No.: HY-139324 Cat. No.: HY-111379Cu(II)GTSM, a cell-permeable Cu-complex,significantly inhibits GSK3. Cu(I

48、I)GTSM inhibitsAmyloid- oligomers (AOs) and decreases tauphosphorylation. Cu(II)GTSM also decreases theabundance of Amyloid- trimers. Cu(II)GTSM is apotential anticancer and antimicrobial agent.EHT 5372 is a highly potent and selectiveinhibitor of DYRKs family kinases with IC s of500.22, 0.28, 10.8,

49、 93.2, 22.8, 88.8, 59.0, 7.44,221 nM for DYRK1A, DYRK1B , DYRK2 DYRK3 CLK1,CLK2, CLK4, GSK-3, GSK-3.Purity: 98%Clinical Data: No Development ReportedSize: 1 mg, 5 mgPurity: 98%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg HYPERLINK https:/www.MedChemE/gnf4877.html GNF

50、4877Cat. No.: HY-129492 HYPERLINK https:/www.MedChemE/BIO.html GSK HYPERLINK https:/www.MedChemE/BIO.html HYPERLINK https:/www.MedChemE/BIO.html 3 HYPERLINK https:/www.MedChemE/BIO.html HYPERLINK https:/www.MedChemE/BIO.html Inhibitor HYPERLINK https:/www.MedChemE/BIO.html HYPERLINK https:/www.MedCh

51、emE/BIO.html IX(6-Bromoindirubin-3-oxime; BIO; MLS 2052) Cat. No.: HY-10580GNF4877 is a potent DYRK1A and GSK3 inhibitorwith IC s of 6nM and 16nM, respectively, which50leads to blockade of nuclear factor of activatedT-cells (NFATc) nuclear export and increased-cell proliferation (EC of 0.66M for mou

52、se50 (R7T1) cells).GSK 3 Inhibitor IX (6-Bromoindirubin-3-oxime;BIO) is a potent, selective, reversible andATP-competitive inhibitor of GSK-3/ andCDK1-cyclinB complex with IC s of 5 nM/320 nM/8050nM for (GSK-3/)/CDK1/CDK5, respectively.Purity: 98.85%Clinical Data: No Development ReportedSize: 5 mg,

53、10 mg, 25 mg, 50 mgPurity: 99.74%Clinical Data: Phase 4Size: 10 mM 1 mL, 5 mg, 10 mg, 50 mg HYPERLINK https:/www.MedChemE/gsk-3-inhibitor-1.html GSK-3 HYPERLINK https:/www.MedChemE/gsk-3-inhibitor-1.html HYPERLINK https:/www.MedChemE/gsk-3-inhibitor-1.html inhibitor HYPERLINK https:/www.MedChemE/gsk

54、-3-inhibitor-1.html HYPERLINK https:/www.MedChemE/gsk-3-inhibitor-1.html 1 HYPERLINK https:/www.MedChemE/gsk-3-inhibitor-1.html HYPERLINK https:/www.MedChemE/gsk-3-inhibitor-xiii.html GSK-3 HYPERLINK https:/www.MedChemE/gsk-3-inhibitor-xiii.html HYPERLINK https:/www.MedChemE/gsk-3-inhibitor-xiii.htm

55、l Inhibitor HYPERLINK https:/www.MedChemE/gsk-3-inhibitor-xiii.html HYPERLINK https:/www.MedChemE/gsk-3-inhibitor-xiii.html XIIICat. No.: HY-13973A Cat. No.: HY-112392GSK-3 inhibitor 1 is an inhibitor of GSK-3.GSK-3 Inhibitor XIII is a potent andATP-competitive GSK-3 inhibitor with a K of 24inM.Puri

56、ty: 99.89%Clinical Data: No Development ReportedSize: 10 mM 1 mL, 5 mg, 10 mg, 50 mg, 100 mgPurity: 98%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 25 mg HYPERLINK https:/www.MedChemE/gsk-3-cdk5-cdk2-in-1.html GSK-3/CDK5/CDK2-IN-1 HYPERLINK https:/www.MedChemE/gsk-3-cdk5-cdk2-in-1.html H

57、YPERLINK https:/www.MedChemE/gsk-3-beta-inhibitor-1.html GSK-3 HYPERLINK https:/www.MedChemE/gsk-3-beta-inhibitor-1.html HYPERLINK https:/www.MedChemE/gsk-3-beta-inhibitor-1.html inhibitor HYPERLINK https:/www.MedChemE/gsk-3-beta-inhibitor-1.html HYPERLINK https:/www.MedChemE/gsk-3-beta-inhibitor-1.

58、html 1Cat. No.: HY-134622 Cat. No.: HY-126144GSK-3/CDK5/CDK2-IN-1, an imidazole derivative,is an inhibitor of cdk5, cdk2, and GSK-3extracted from patent WO2002010141A1, example 9a.GSK-3/CDK5/CDK2-IN-1 can be used for the researchof cancer, and neurodegenerative diseases.GSK-3 inhibitor 1 (compound 3

59、a) is a glycogensynthase kinase 3 (GSK-3) inhibitor anddemonstrates high antidiabetic efficacy, with anIC of 4.9 nM.50Purity: 98.56%Clinical Data: No Development ReportedSize: 10 mM 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mgPurity: 98.07%Clinical Data: No Development ReportedSize: 10 mM 1 mL, 5 mg, 10

60、mg, 50 mg6 Tel: 609-228-6898 Fax: 609-228-5909 Email: salesMedChemE HYPERLINK https:/www.MedChemE/gsk-3-inhibitor-2.html GSK-3 HYPERLINK https:/www.MedChemE/gsk-3-inhibitor-2.html HYPERLINK https:/www.MedChemE/gsk-3-inhibitor-2.html inhibitor HYPERLINK https:/www.MedChemE/gsk-3-inhibitor-2.html HYPE