Helioxanthin-8-1-Helioxanthin-analogue-8-1-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEHelioxanthin 8-1Cat. No.: HY-16680CAS No.: 840529-13-7Synonyms: Helioxanthin analogue 8-1分式: CHNO分量: 376.32作靶點: HBV作通路: Anti-infection儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 10 mg/m

2、L (26.57 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 2.6573 mL 13.2866 mL 26.5731 mL5 mM 0.5315 mL 2.6573 mL 5.3146 mL10 mM 0.2657 mL 1.3287 mL 2.6573 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內(nèi)實驗 請根據(jù)您的實驗動物和給藥式選擇適當(dāng)?shù)娜芙獍福渲魄罢埾扰渲瞥吻宓膬湟?，再依次添加助溶?為保證實驗結(jié)果的可靠性，體內(nèi)實驗的作液，建議您現(xiàn)現(xiàn)配

3、，當(dāng)天使；澄清的儲備液可以根據(jù)儲存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 1 mg/mL (2.66 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 1 mg/mL (2.66 mM); Clear solution1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEBIOL

4、OGICAL ACTIVITY物活性 Helioxanthin 8-1是helioxanthin類似物，具有抗HBV/HCV/HSV-1/HIV的活性，EC50分別為5/10/1.4/15uM。戶使本產(chǎn)品發(fā)表的科研獻 ACS Infect Dis. 2019 May 10;5(5):778-787.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Yeo H, et al. Synthesis and antiviral activity of helioxanthin analogues. J Med

5、Chem. 2005 Jan 27;48(2):534-46.2. Ying C, et al. Helioxanthin analogue 8-1 inhibits duck hepatitis B virus replication in cell culture. Antivir Chem Chemother. 2010;21(2):97-103.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-58955