(21)-執(zhí)業(yè)藥師藥劑學LiquiddosageformsI

I.LiquiddosageformsI采用熱熔法制備單糖漿、并制備混懸劑爐甘石洗劑和磺胺嘧啶合劑，通過測定沉降體積比，比較混懸劑中各添加劑的作用。PurposeTomasterthebasicmethodsofsolutionpreparation.Tomasterthegeneralpreparationmethodsofsuspensions.Equipmentsandmaterials1.EquipmentsBeaker(500ml),glassfilter(6cm.10cm),graduatedcylinder(100ml),balance,glassstick.filterpaper.electricfurnace,mortarandpestle,measuringgylinder2.MaterialsSucrose,distilledwater,calamine,zincoxide,glycerol,sodiumcitrate,aluminumchloride,CMC-Naetc.Procedures1.SimplesyrupSucrose85gDistilledwateraddto100mlSucrosewasdissolvedwith45miofdistilledwater.Thesolutionwasthenfilteredthroughrefinedcottonimmediatelyafterboiling.Finally,addtheremainingwatertothefilteredsolutionthroughthecolanderandmix.2.CalaminelotionsFivekindsofsampleswerepreparedaccordingtothefollowingtable.Compositiongroup1group2group3group4group5Calamine(120mesh),g44444Zincoxide(120mesh),g44444Glycerol,ml55555CMC-Na,g0.25Aluminumchloride,g0.15%Bonzalkoniumbromide,ml0.1Sodiumcitrate,g0.25Waterad.ml5050505050Calaminelotionswerepreparedbygrindingmethodwhileaddingliquid.Determinationofsedimentationvolume(F)ofcalaminelotionsPlacefivekindsoflotionsintofive50mlmeasuringcylinderswithstopperrespectively.Stopperthemeasuringcylindersandshakefor1min.eachoriginalheightH0waswrittendown.Afterspecifiedintervals,theheightsofsedimentationHuwererecordedintoTab1-2.Sedimentationcurvewasplotted,F(F=Hu/H0)astheordinateandtimetastheabscissa.3.sulfadiazinemixturesSulfadiazine10gSodiumhydroxide1.6gCitricacid3gSodiumcitrate6.5gSodiumbenzoate0.2g1%SodiumsaccharinQ.SFlavorQ.SDistilledwateraddto100mlThelotionswerepreparedbymicro-crystallizationmethod.QuestionsWhatarethefunctionsofvariousingredientsineachformulationofthisexperience?Whichingredientineachformulat