Inosine _Endogenous Metabolite - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEInosineCat. No.: HY-N0092CAS No.: 58-63-9分式: CHNO分量: 268.23作靶點(diǎn): Endogenous Metabolite作通路: Metabolic Enzyme/Protease儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 9.66 mg/mL (36.01 mM; Need

2、 ultrasonic and warming)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 3.7281 mL 18.6407 mL 37.2814 mL5 mM 0.7456 mL 3.7281 mL 7.4563 mL10 mM 0.3728 mL 1.8641 mL 3.7281 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Inosine個(gè)個(gè)內(nèi)源性嘌呤核苷，有免疫調(diào)節(jié)，神經(jīng)保護(hù)、鎮(zhèn)痛等特性。IC50 & Target Human Endo

3、genous MetaboliteREFERENCES1. Moore TL et al. Inosine enhances recovery of grasp following cortical injury to the primary motor cortex of the rhesus monkey. Restor1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemENeurol Neurosci. 2016 Aug 1.2. Welihinda AA et al. The adenosine metabolite inosine is a

4、 functional agonist of the adenosine A2A receptor with a unique signaling bias.Cell Signal. 2016 Jun;28(6):552-60.3. Junqueira SC et al. Inosine, an Endogenous Purine Nucleoside, Suppresses Immune Responses and Protects Mice from ExperimentalAutoimmune Encephalomyelitis: a Role for A2A Adenosine Receptor. Mol Neurobiol. 2016 Apr 30.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax