Pefloxacin-mesylate-Pefloxacinium-mesylate-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEPefloxacin mesylateCat. No.: HY-B0147ACAS No.: 70458-95-6Synonyms: Pefloxacinium mesylate分式: CHFNOS分量: 429.46作靶點(diǎn): Bacterial作通路: Anti-infection儲(chǔ)存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) H2O :

2、100 mg/mL (232.85 mM)DMSO : 12.5 mg/mL (29.11 mM; Need ultrasonic)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 2.3285 mL 11.6425 mL 23.2851 mL5 mM 0.4657 mL 2.3285 mL 4.6570 mL10 mM 0.2329 mL 1.1643 mL 2.3285 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限

3、。體內(nèi)實(shí)驗(yàn)請(qǐng)根據(jù)您的實(shí)驗(yàn)動(dòng)物和給藥式選擇適當(dāng)?shù)娜芙獍?，配制前?qǐng)先配制澄清的儲(chǔ)備液，再依次添加助溶劑(為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄清的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請(qǐng)依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 1.25 mg/mL (2.91 mM); Clear solution2. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)1/2 Master of Small

4、 Molecules 您邊的抑制劑師www.MedChemESolubility: 1.25 mg/mL (2.91 mM); Clear solution3. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 1.25 mg/mL (2.91 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Pefloxacin是抗菌化合物，通過抑制DNA旋轉(zhuǎn)酶來阻斷DNA復(fù)制。戶使本產(chǎn)品發(fā)表的科研獻(xiàn) Chemosphere. 2019 Mar.See more customer validations on HYPERLINK / w

5、ww.MedChemEREFERENCES1. Drlica K, et al. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92.2. Hussy P, et al. Effect of 4-quinolones and novobiocin on calf thymus DNA polymerase alpha primase complex, topoisomerases I and II,and growth of mammalian lymphoblasts. Antimicrob Agents Chemother. 1986 Jun;29(6):1073-8.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;