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QUINTANATURACEUTICALS
Summary:QuintaNaturaceuticals,INCProduct:H.RoseaPillMitigatesinflammation,diabetes,cancer,andneurodegenerativediseasesMissionThemissionofQuintaistogrowplantsthataresourcesofnovel,well-tolerated,non-toxicandorallybio-availableeffectivetherapeuticagentsforuseinthetreatmentofcancer,inflammatory,neurodegenerative,andparasiticdiseases.
MarketMarketCompetition2,616healthfoodmanufacturingenterprisesinChinain2013*.Largeenterprises(+Rmb100million)=~2%ofthemarket.China’s12thFive-YearPlanfortheFoodIndustry:10+firmsRmb10B+ayeartop100enterprisesintheindustrycontrol50%+2008-Amway,AvongrantedapprovalbyChinaforhealthfoodProcter&Gamble,Johnson&Johnson,Herbalife,Pfizer&GlaxoSmithKlineactivelydevelopingChinahealthfoodandnutritionalsupplementmarket.Currently,inthetraditionalhealthfoodmarket,leadingenterprisesincludingWanji,Goldensun,Infinitus,HongFuLoiandDong-EE-Jiaoaccountforthelion’sshare.Inthefunctionalhealthfoodmarket,ShanghaiJiaodaOnllyisoneofthemajorsuppliers *SFDA’sFood&DrugStatisticalYearbook2013MarketSegmentationAsofJuly2015,theStateFoodandDrugAdministration(SFDA)hadapprovedatotalof15,802healthfoodproducts,ofwhich,15,063weredomesticallymadeand739wereimported.Accordingtoestimates,inChina’shealthfoodmarket,functionalfoodaccountsforabout65%whilenutritionalsupplementsaccountfortheremaining35%.(HKTDCResearch24Sep2015)Ifourproducttook1/17,000shareofthismarket:~Rmb58.8M/year1%ofthenutritionalsupplementmarketwouldbe~Rmb3.5B/year1HypoestesroseaProductHYPOESTOXIDEISAUNIQUENON-TOXIC,ORALLYBIOAVAILABLENATURALPRODUCTFROMNATURALBIO-RESOURCESUSEDINNIGERIAFORGENERATIONSHYPOESTOXIDEHASUNDERGONEYEARSOFEXTENSIVELABORATORYTESTINGWITHINDEPENDENTCOLLABORATORSHYPOESTOXIDEHASFOURLARGEMARKETSEGMENTS:INFLAMMATION,CANCER,MALARIA,PARKINSON’SDISEASE&OTHERNEURODEGENERATIVEDISEASESSoldintheUSAforResearchPurposesbycompaniessuchasSantaCruzBiotechnology(SCBT)EMDMillipore(MERCK)
ManagementEmekaJ.Nchekwube,M.D.,CEOandMedicalDirector
practicingneurosurgeoninSiliconValley,Californiawithover30yearsexperience.
HealsoservesasChiefofNeurosurgeryatRegionalMedicalCenter,anawardwinninghospitalinthelargestcityinSiliconValley,ResearchScientistwith4patentsandonependingUcheNchekwube,M.B.A.
CFOConsultantwith10+yearsofexperienceworkingwithforandnon-profitcompaniesonbusinessdevelopmentDonnaNchekwube,M.D.
corporatesecretaryResearchScientistwith4patentsandonepending
ScientificResearchImmuneModulation,INC
HasresearchedandpatentedHypoestoxide,extractedfromHypoestesroseaAndalsodirectedallcollaboratorsOnthepathtoFDAapprovalHYPOESTOXIDELOWERSHIGHBLOODCHOLESTEROLANDTRIGLYCERIDELEVELSINDOGSDays-113714NormalReferenceRangeCholesterol(mg/dl)308122130124134(92-324)Triglycerides(mg/dl)300296703351(29-291)A2-year-old10kgfemalebeagledogwasorallydosedwith30mg/kgpurehypoestoxide,oncedailyfor7days.Bloodcholesterolandtriglyceridelevelsweredeterminedinseraobtainedonthedaysindicatedontable.ConsumptionofHRoseaPill
LowersTriglycerideLevelsinHumanSubjectsCosmeticIndications
H.roseaextractofdriedleafpowdermaybeusedinacosmeticcompositionfor:PreventionofallergicreactionResolutionofinfectioninacneResolutionofpsoriaticplaquesAlleviationofUV-inducedskinirritationReduction/PreventionofprematureskinagingEvaluationofCrudeHypoestoxideExtractOnHumanSubjectswithAcneINVIVODATA(COLONCANCER)AIM:EvaluateHypoestoxideonthegrowthofestablished coloncancerinmice.
METHODS:CT26coloncancer-inducedBALB/cmicewere used RESULTS:MeanTumorvolumeforHE-treated=471.2mm3 versus1,542.8mm3forcontrol
(P<0.01).
Mean
TumorvolumeforHE+5-FU=486mm3CONCLUSION:Hypoestoxideisaneffectivetherapeuticagentforcolorectalcancerinmice.Hypoestoxideand5-FUmaybeusedincombination.OpportunityQuintaseeksapartnertodevelopandservetheChineseNutritionalSupplementMarketPurchaseallrightsupfrontQuintawillsupplyinitialinventoryanddeveloplocalChinesegrowthanddevelopmentofHypoestisRoseagreenhousesandproductmanufacturingInvestmentOpportunityImmuneModulationIncorporatedseeksFDAapprovalofdrugNutritionalSupplementMarketinUSdeterminedtounderminetheendeav
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