生物專業(yè)細(xì)胞生物學(xué)課程試題5

1、生物專業(yè)細(xì)胞生物學(xué)課程試題（5）一、選擇填空（每小題2分，共60分，請做在答題卡上）1The first man that described the cell structures is   A. Robert Hook. B. van Leeuwenhoek. C. W. Flemming. D. J. E. Pukinye. 2Phase contrast microscope can be used to observe   A.     Alive cell.B.   

2、60; Stained cell.C.    Not stained cell.D.    All of the above.3If you wanted to separate eukaryote ribosomal subparticles by size, which of the following techniques would you use?   A.     Gel electrophoresis. B.   

3、0; Radiolabelling.C.    Polymerase chain reaction.D.    Density gradient centrifugation.4Which of the following description about prion in not true?   A. Prion is a sort of protein that causing some severe diseases, such as bovine sponge-form encephalopathies

4、(BSM, mad cow disease). B. Prion can replicate itself by change the conformation of the proteins which are similar to prion. C. Prion is a transcription regulatory protein. D. Prion was discovered by Prusiner in 1982. 5In general, glycoproteins and glycolipids:   A. Are on the outer leafle

5、t of the unit membrane, facing the environment of a cell. B. Are on the inner leaflet of the unit membrane, facing the cytosol. C. Are equally distributed on the inner and outer surface of the unit membrane. D. Occur only in internal membranes. 6Which of the following is not the function of the bio-

6、membrane?   A. Signal transduction. B. Transportation. C. Transcription. D. Compartmentalization. 7In human intestine glucose are absorbed by the way of   A. Na+ powered antiport. B. Na+ powered symport. C. Channel proteins. D. ABC transporter. 8The Na+/K+ ATPase of eukaryotic ce

7、lls   A. Is a P-type pump. B. Is a V- type pump. C. Is an F- type pump. D. Is an ATP-binding cassette. 9Following organelles are all surrounded by double bio-membranes except    A. Mitochondrion B. Chloroplast. C. ER. D. Nucleus. 10"Cis," "medial "and &qu

8、ot;trans " specify different compartments of the.A. Golgi body. B. Endoplasmic reticulum. C. Mitochondrion. D. Nucleus. 11The PH value in lysosome is lower than that in cytoplasm because lysosome membrane exist   A. P-type H+ pump. B. F-type H+ pump. C. V-type H+ pump. D. P-type Na+-K

9、+ pump. 12Which of the following statements about signal sequences is false?    A. Signal sequences are removed from protein by signal peptidase after the sorting process has been completed (except nuclear localization sequence (NLS) and signal patch). B. Each signal sequence specifie

10、s a particular destination in the cell. C. NLS direct proteins into cytoplasm from nucleus. D. Any protein with a proper signal sequence will be transferred into the peroxisome. 13Which of the following about peroxisomes is true   A. They are formed by binary fission of existing peroxisome

11、s. B. They contain their own DNA. C. They contain oxidative enzymes. D. Both A and C 14PSI absorb light of wavelength at   A.     680nm.B.     700nmC.    280nmD.    Both A and B15Which of the following is not encoded by

12、the mtDNA?   A. Cytochrome c. B. Cytochrome b. C. F0. D. Keratin. 16Cyclic photophosphorylation is accomplished by   A. Photosystem I. B. Photosystem II. C. Photosystem III. D. Both photosystems I and II. 17G-protein linked receptors are    A. Single-pass transmemb

13、rane proteins. B. Seven-pass transmembrane proteins. C. Three-pass transmembrane proteins. D. Not a transmembrane protein. 18Which of the following is NOT a second messenger?    A. NO. B. cGMP. C. cAMP. D. IP3. 19Dyneins are motor proteins that move from   along   

14、 A. end to +end; microtubules. B. +end to end; microtubules. C. end to +end; microfilaments. D. +end to end; microfilaments. 20Microtubules function in cells   A. As structural supports, maintaining the shape of the cell. B. To form the spindle during mitosis and meiosis. C. As a part

15、 of the system that causes movement in cilia and flagella. D. All of the above. 21Functions of tight junctions include all the following except    A. Separation of extracellular fluid. B. Sealing of body cavities. C. Prevention of diffusion of membrane proteins and lipids between apic

16、al and basolateral regions. D. Tight communication and extrange of small molecules between neighboring cells. 22Which of the following cytoskeleton structures links to desmosomes and hemidesmosomes?    A. Microtubules. B. Intermediate filaments. C. Microfilaments. D. all of the above.

17、 23Cell binding domain in fibronectins contain   A. RGD sequences. B. KDEL sequences. C. Gly-XY sequences. D. PEST sequences. 24The core proteins in nucleosome are   A. H2A, H2B, H3, H4. B. H1A, H1B, H3, H4. C. H1A, H2A, H3, H4. D. H1, H2, H3, H4. 25Eukaryotic chromosomes contain

18、 two general domains which relate to the degree of condensation. These two regions are   A. Uniform in the genetic information they contain. B. Called heterochromatin and euchromatin. C. Separated by large stretches of repetitive DNA. D. Both A and B 26What is the main function of cyclin p

19、roteins?   A. They initiate a signal transduction cascade that leads to changes in the cells behavior. B. They regulate the cell division by binding and activating CDK enzymes. C. They are the main protein components of the kinetochore. D. They block cell cycle progression when conditions

20、are not appropriate for growth. 27MPF consists of  A. CDC2 and cyclin D B. CDC2 and cyclin E C. CDC2 and cyclin B D. CDK1 and cyclin C 28Necrosis   A. May be mediated by FAS signal pathway. B. Characterized by DNA degraded into about 200bp fragment. C. Is a genetically controlled proc

21、ess. D. Occurs when cell is injured. 29Which of the following mutations in a tumor suppressor gene will most likely not result in cancer?   A. Point mutant. B. Deletion. C. Gene rearrangement. D. All of the above. 30Which of the following about apoptosis is not true?   A. Is accompanied by random DNA degradation. B. Is a sort of "cellular self-destruction" that takes place in normal tissues. C. Is characterized by nuclear fragmentation and