Hydroxytyrosol-DOPET-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEHydroxytyrosolCat. No.: HY-N0570CAS No.: 10597-60-1Synonyms: DOPET; 3,4-Dihydroxyphenethyl alcohol; 3-Hydroxytyrosol分式: CHO分量: 154.16作靶點(diǎn): Others作通路: Others儲(chǔ)存式: Pure form -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month

2、溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 125 mg/mL (810.85 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 6.4868 mL 32.4338 mL 64.8677 mL5 mM 1.2974 mL 6.4868 mL 12.9735 mL10 mM 0.6487 mL 3.2434 mL 6.4868 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。體內(nèi)實(shí)驗(yàn)請(qǐng)根據(jù)您的實(shí)驗(yàn)動(dòng)物和給藥式選擇適當(dāng)?shù)娜芙獍?，配制前?qǐng)先配制澄的儲(chǔ)備液，再依次添加助溶劑(為

3、保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請(qǐng)依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (13.49 mM); Clear solution2. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.08 mg/mL (13.49 mM); Clear solution3. 請(qǐng)依序添加每種溶劑： 10% DMS

4、O 90% corn oil1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemESolubility: 2.08 mg/mL (13.49 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Hydroxytyrosol (DOPET)從橄欖樹(shù)及其葉中提取的種酚類化合物，具有抗氧化、抗動(dòng)脈粥樣硬化、抗栓、抗 、抗炎和抗腫瘤的作 1 2。體外研究 Hydroxytyrosol (DOPET) shows the inhibition of pro-inflammatory cytokines (TNF-) and re

5、duces theexpression of cyclooxygenase-2 and inducible nitric oxide synthase (iNOS) more than 60% 1.Hydroxytyrosol (DOPET) modulates the transcription factor NF-B 1.Hydroxytyrosol (DOPET) arrests thecell cycle, producing differentiation, apoptosis, or preventing DNA from oxidative stress 1.REFERENCES

6、1. Vilaplana-Prez C, et al. Hydroxytyrosol and potential uses in cardiovascular diseases, cancer, and AIDS. Front Nutr. 2014 Oct 27;1:18.2. Martnez L, et al. Hydroxytyrosol: Health Benefits and Use as Functional Ingredient in Meat. Medicines (Basel). 2018 Jan 23;5(1).McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400