參考分析微生物-6bacteria

MedicalDepartmentofMicrobiology,SectionSectionIIIPathogenesisofBacterialZhao-HuaZhong,Ph.D.,Prof.Dept.ofMicrobiology,HMUBacterialManytypesMechanismsofbacterialAdherence:Fimbriae,afimbriaeInvasionfactors:enzymes,capsules,Exotoxins& KeyKeyOpportunisticInfectiousKoch’s

Extra/intracellularCompromisedAmicroorganismcapableofcausingIdentifyingIdentifyingBacteriaThatCauseDisease:Koch'spostulatesMolecularKoch’sMolecularKoch’sKnock-Knock-downExceptionsExceptionstoKoch’sTreponemapallidumMycobacteriumlepraenotbeNesseriagonorrhoeaeanimalmodelforitsE.coli(foodpoisoning,benormalflora,butcausediseaseswhenmovingtootherorgansMechanismsMechanismsofBacterialHostHostRespiratoryUrogenitalNormalskinandmucousmembranesprovidetheprimarydefenseagainstTocausedisease,pathogensmust thesebarriersBacterialBacterialVirulenceInvasionInvasionofhostcells&AntiphagocyticInvasiveIntracellularMicrocolony,E.coliwithE.E.coliStreptococcusStreptococcusInvasiveTissue-degradingCosmeticIgA

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Horizontaltransmissionofabacterial,fungal,orviralinfectionbetweenmembersofthesamespeciesthatarenotinaparent-childTypesTypesofBacterialExogenousExogenousEndogenousInapparentSubclinicalApparentAcuteChoronicLocalSystemicTypesoftoilBacterial菌血

毒血

內毒素血

敗血

膿毒 ThepresenceofbacteriaintheThedetectionofbacteriainthebloodisalwaysabnormalToxemia/bacteriaitselfmaynotenterorgrowintheSepticemiaPyemia敗血癥/ 敗血Adiseasecausedbythepresenceofpathogenicbacteriainthebloodstream,characterizedbychillsandfever 膿毒血typeofsepticaemiathatleadswidespreadabscessesofametastatictheblood,e.g.StaphylococcusSectionSectionIIIAntimicrobialImmune PathogenAlveolarMacrophageAttackingE.Defensespecific

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